基于频繁模式增长算法的重症监护室转出率预测模型研究

Prediction model of transfer rate of intensive care unit patients based on frequent pattern growth algorithm

  • 摘要:
    目的 基于频繁模式增长(FP-Growth)算法构建重症监护室(ICU)患者转出率预测模型,并评价该模型的应用价值。
    方法 选取ICU患者4 000例为研究对象,将其分为建模组和验证组。收集并比较2组的临床资料。建模组行基于FP-Growth算法的关联规则分析。通过计算建模组最终扫描集合元素间有效强关联规则,构建ICU患者转出率预测模型。在内部验证中,通过校准曲线等评价模型的一致性。在外部验证中,比较建模组和验证组预测ICU患者转出率的受试者工作特征(ROC)曲线的曲线下面积(AUC)。
    结果 建模组患者在同时具备相应临床资料的前提下, 7 d内转出率为71%, >7~14 d内转出率为40%, >14~21 d内转出率为18%。在内部验证中,校正曲线显示,预测值与观测值的一致性较为理想。在外部验证中,模型预测建模组7 d、>7~14 d、>14~21 d转出率时的AUC分别为0.880、0.861、0.654。
    结论 ICU患者转出率预测模型的短期(14 d内)预测效能较为理想,其应用对优化ICU整体治疗效果和医疗资源配置具有一定的参考意义。

     

    Abstract:
    Objective To construct a prediction model for the transfer-out rate of patients in the intensive care unit (ICU) based on frequent pattern growth (FP-Growth) algorithm and evaluate its application value.
    Methods A total of 4, 000 ICU patients were selected as study subjects and divided into model construction group and validation group. Clinical data from both groups were collected and compared. Association rule analysis based on the FP-Growth algorithm was performed in the model construction group. A prediction model for the ICU patient transfer-out rate was established by calculating effective strong association rules among the elements in the final scanned set of the model construction group. In internal validation, the model′s consistency was evaluated using calibration curves and other metrics. In external validation, the area under the receiver operating characteristic (ROC) curve (AUC) for predicting the ICU patient transfer-out rate was compared between the model construction group and the validation group.
    Results In the model construction group, with corresponding clinical data available, the transfer-out rates within 7 days, > 7 to14 days, and > 14 to 21 days were 71%, 40% and 18%, respectively. During internal validation, the calibration curve demonstrated satisfactory consistency between predicted and observed values. In external validation, the AUC values for the model′s predictions of transfer-out rates at 7 days, > 7 to14 days, and > 14 to 21 days in the model construction group were 0.880, 0.861 and 0.654, respectively.
    Conclusion The prediction model for the ICU patient transfer-out rate exhibits favorable short-term (within 14 days) predictive performance, and its application holds certain reference value for optimizing the overall treatment efficacy in the ICU and the allocation of medical resources.

     

/

返回文章
返回