心房颤动射频消融术后心电散点图、瀑布图形态特征与心电参数分析及临床意义

Morphological characteristics of electrocardiographic scatter plots, waterfall plots and electrocardiographic parameters after radiofrequency ablation in patients with atrial fibrillation and their clinical significance

  • 摘要:
    目的 探讨心房颤动(简称房颤)患者射频消融术后心电散点图、瀑布图形态特征与心电参数及其临床意义。
    方法 回顾性选取156例接受射频消融治疗的房颤患者作为研究对象, 术后随访12个月。根据随访期间动态心电图及远程心电监测结果,将患者分为窦性心律维持组101例和房颤复发组55例。收集所有患者的基线资料、心电图形态特征(Lorenz散点图形态、瀑布图带状分布)、心电参数平均心室率、正常窦性心搏间期标准差(SDNN)、24 h房性早搏次数、瀑布图离散程度、左心房直径等,采用单因素和多因素Logistic回归分析筛选房颤复发的影响因素,绘制受试者工作特征(ROC)曲线分析心电图形态特征和心电参数对术后房颤复发的预测效能。
    结果 房颤复发组Lorenz散点图残留扇形占比高于窦性心律维持组,差异有统计学意义(P < 0.05); 2组SDNN、瀑布图离散程度、左心房直径比较,差异有统计学意义(P < 0.001)。多因素Logistic回归分析显示,残留扇形(OR=1.950, 95%CI: 1.210~3.121)、瀑布图离散程度>0.3(OR=1.692, 95%CI: 1.182~2.424)、左心房直径>40 mm(OR=2.061, 95%CI: 1.120~3.795)、SDNN < 100.15 ms(OR=1.943, 95%CI: 1.256~3.011)是房颤复发的独立危险因素(P < 0.05)。ROC曲线分析显示,残留扇形、瀑布图离散程度、左心房直径、SDNN联合预测房颤复发的曲线下面积(AUC)为0.909, 大于4项指标单独预测的AUC, 差异有统计学意义(P < 0.001)。
    结论 房颤患者射频消融术后,心电散点图“残留扇形”特征、瀑布图离散程度、左心房直径及SDNN均为房颤复发的影响因素,四者联合预测的效能优于单独预测,可为临床提供更精准的术后风险分层工具。

     

    Abstract:
    Objective To explore the morphological characteristics of electrocardiographic scatter plots, waterfall plots and electrocardiographic parameters, and their clinical significance in patients with atrial fibrillation after radiofrequency ablation.
    Methods A total of 156 atrial fibrillation patients who received radiofrequency ablation treatment were retrospectively selected as the study subjects and followed up for 12 months postoperatively. According to the results of dynamic electrocardiogram and remote electrocardiographic monitoring during the follow-up period, the patients were divided into sinus rhythm maintenance group (101 cases) and atrial fibrillation recurrence group (55 cases). Baseline data, electrocardiographic morphological characteristics (Lorenz scatter plot morphology, waterfall plot band distribution), and electrocardiographic parameters average ventricular rate, standard deviation of normal-to-normal intervals (SDNN), number of 24-hour atrial premature beats, waterfall plot dispersion, left atrial diameter, etc. were collected from all patients. Univariate and multivariate logistic regression analyses were used to screen for factors influencing atrial fibrillation recurrence. Receiver operating characteristic (ROC) curves were plotted to analyze the predictive efficacy of electrocardiographic morphological characteristics and electrocardiographic parameters for postoperative atrial fibrillation recurrence.
    Results The proportion of residual sectors in the Lorenz scatter plot was higher in the atrial fibrillation recurrence group than that in the sinus rhythm maintenance group, with a statistically significant difference (P < 0.05). There were statistically significant differences in SDNN, waterfall plot dispersion, and left atrial diameter between the two groups (P < 0.001). Multivariate logistic regression analysis showed that residual sectors (OR=1.950, 95%CI, 1.210 to 3.121), waterfall plot dispersion>0.3 (OR=1.692, 95%CI, 1.182 to 2.424), left atrial diameter>40 mm (OR=2.061, 95%CI, 1.120 to 3.795), and SDNN < 100.15 ms (OR=1.943, 95%CI, 1.256 to 3.011) were independent risk factors for atrial fibrillation recurrence (P < 0.05). ROC curve analysis showed that the area under the curve (AUC) for the combined prediction of atrial fibrillation recurrence by residual sectors, waterfall plot dispersion, left atrial diameter, and SDNN was 0.909, which was greater than the AUC for each indicator alone, with a statistically significant difference (P < 0.001).
    Conclusion After radiofrequency ablation in atrial fibrillation patients, the "residual sector" characteristic of the electrocardiographic scatterplot, waterfall plot dispersion, left atrial diameter, and SDNN are all factors influencing atrial fibrillation recurrence. The combined predictive efficacy of these four factors is superior to that of individual prediction, providing a more accurate postoperative risk stratification tool for clinical practice.

     

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