The effect analysis of nursing intervention on adverse reactions of patients with uremia combined with HCV infection treated by interferon during hemodialysis period

Objective To analyze adverse reactions of patients with uremia combined with HCV infection treated by interferon during hemodialysis period and to explore the cure rate of nurs-ing intervention.Methods 9 patients with HCV during hemodialysis period were injected with subcutaneous interferon for 6 months.The adverse reactions during treatment were given individu-alized nursing measures during dialysis.Quantitative indicators of virus were detected after 3 months,6 months and 6 months after the drugs stopped.Results There were 7 patients complet-ed the treatment and 2 patients discontinued treatment due to side effects.Early response rate was 78%.ALT in serum in 78%patients was normal at the end of treatment,HCV-RNA in serum was negative (<1000 /ml).Sustained response rate of follow-up was 100% after 6 months.Conclusion Individualized nursing for dialysis patients with HCV treated by interferon could significantly improve treatment compliance and achieve clinical cure efficacy.