Effect of valsartan combined with amlodipine on the level of blood sugar,serum lipid and blood uric acid of elderly patients with hypertension complicated with diabetics

Objective To explore clinical efficacy of valsartan combined with amlodipine on the level of blood sugar,serum lipid and blood uric acid of elderly patients with hypertension compli-cated with diabetics.Methods A total of 120 cases with hypertension complicated with diabetics were selected and divided into 2 groups.Combined-used group was given oral valsartan combined with amlodipine and single-amlodipine group was given amlodipine.Clinical efficacy and indexes of serum lipid,fasting blood-glucose (FBG),fasting insulin (FINS),insulin sensitivity index (ISI) and blood uric acid (UA)were observed.Results Total effective rate of combined-used group was 93.33% and single-amlodipine group was 80.00%,there was significant difference between 2 groups (P >0.05).there were no differences in the levels of serum lipid,FBG,FINS and ISI be-fore treatment (P >0.05).And the above mentioned indexes were significantly changed after treatment (P < 0 .0 1 ).there were no differences in single-amlodipine group before treatment (P >0.05).Conclusion The clinical effect of valsartan combined with amlodipine for treating el-derly patients with hypertension complicated with diabetics be superior to single-amlodipine group and can obviously improve fat metabolism and insulin sensitivity.