Evaluation of lactic acid level in blood and its clearance rate in the prognosis of patients with infectious shock

Objective To discuss the evaluation value of blood lactic acid level and its clear-ance rate in the prognosis of patients with infectious shock.Methods The clinical data of 88 pa-tients with infectious shock in our hospital from May 2011 to October 2013 were retrospectively ana-lyzed and divided into survival group (48 cases)and death group (40 cases)according to whether the patients were alive or dead after 28 d of hospitalization.The blood lactic acid level,clearance rate of lactic acid as well as Acute Physical and Chronic Health Evaluation Ⅱ (APACHEⅡ)at 6 and 24 h after hospitalization,the survival rate of patients with different clearance rates of lactic acid after 6 h,and the relationship between blood lactic acid level and its clearance rate with the progno-sis were observed.Results There was no significant differences between two groups in the initial level of lactic acid (P >0.05).Survival group was apparently lower in blood lactic acid levels at 6 and 24 h (P <0.01)and obviously higher in their clearance rates than death group (P <0.01). The survival rates of patients with clearance rate ≥10% in 6 h was 91.49%,evidently higher than that of in patients (12.20%)with 6 h clearance rate <10% (P <0.01).Multiple linear regression analysis showed that the clearance rate of lactic acid at 6 and 24 h were the independent influencing factors of patients’death (P <0.01).Conclusion Dynamic detection of blood lactic acid has criti-cal significance in patients with infectious shock,and the clearance rates of lactic acid at 6 and 24 h can be regarded as the main indexes in evaluating patients′prognosis.