Research progress on histone methylation modification in aging cardiovascular disease

Changes in cardiac structure and function such as myocardial aging, valve alterations, alterations in the cardiac conduction system and vascular aging are crucial for studying therapeutic methods for age-related cardiovascular diseases. Histone methylation modification is involved in the regulation of gene expression and closely related to the occurrence and development of age-related cardiovascular diseases. This paper provided a comprehensive review on the role of histone methylation modification in cardiac structural and functional changes, providing new theoretical basis for age-related cardiovascular diseases.