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肺癌患者血清血管内皮生长因子水平与预后及血小板的相关性研究

黄谦, 姜正华, 朱慕云, 桑慧颖, 卞京文, 李昌喜

黄谦, 姜正华, 朱慕云, 桑慧颖, 卞京文, 李昌喜. 肺癌患者血清血管内皮生长因子水平与预后及血小板的相关性研究[J]. 实用临床医药杂志, 2011, (5): 1-4. DOI: 10.3969/j.issn.1672-2353.2011.05.001
引用本文: 黄谦, 姜正华, 朱慕云, 桑慧颖, 卞京文, 李昌喜. 肺癌患者血清血管内皮生长因子水平与预后及血小板的相关性研究[J]. 实用临床医药杂志, 2011, (5): 1-4. DOI: 10.3969/j.issn.1672-2353.2011.05.001
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HUANG Qian, JIANG Zheng-hua, ZHU Mu-yun, SHANG Hui-ying, BIAN Jing-wen, LI Chang-xi. A correlative study of serum levels of vascular endothelial growth factor and prognosis and platelet in patients with lung cancer[J]. Journal of Clinical Medicine in Practice, 2011, (5): 1-4. DOI: 10.3969/j.issn.1672-2353.2011.05.001
Citation: HUANG Qian, JIANG Zheng-hua, ZHU Mu-yun, SHANG Hui-ying, BIAN Jing-wen, LI Chang-xi. A correlative study of serum levels of vascular endothelial growth factor and prognosis and platelet in patients with lung cancer[J]. Journal of Clinical Medicine in Practice, 2011, (5): 1-4. DOI: 10.3969/j.issn.1672-2353.2011.05.001
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肺癌患者血清血管内皮生长因子水平与预后及血小板的相关性研究

  • 江苏省苏北人民医院,呼吸内科,江苏,扬州,225001

详细信息

  • 中图分类号: R734.2

A correlative study of serum levels of vascular endothelial growth factor and prognosis and platelet in patients with lung cancer

摘要

    摘要
  • 摘要: 目的 探讨肺癌患者血清血管内皮生长因子(VEGF)水平及与预后及血小板的相关性.方法 采用酶联免疫吸附法(ELISA)对60例肺癌患者及20例健康人的血清VEGF分别进行测定,同时检测患者全血血小板(PLT)含量.结果 肺癌患者血清VEGF水平显著高于健康对照组(P<0.01),肺癌患者血清VEGF水平与肺癌的病理类型、TNM分期之间无明显关系.肺癌患者血清VEGF水平与其生存期之间呈显著的负相关(r=-0.38.P<0.01),肺癌患者血清VEGF水平与血小板之间呈显著的正相关(r=0.26,P<0.05).结论 肺癌患者血清VEGF水平与患者的预后密切相关,血清VEGF是评估肺癌患者预后的重要指标.肺癌患者血清VEGF水平与PLT水平密切相关,血小板在肿瘤血管形成的过程中可能起重要的作用.
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  • 发布日期:  2011-08-01

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