Correlation analysis of homocysteine and pulse wave velocity in elderly patients with hypertensive cerebral infarction
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摘要: 目的 对老年高血压脑梗死患者血浆同型半胱氨酸(Hcy)水平与动脉脉搏波传播速度(pwv)的相关性进行分析,探讨血浆Hcy水平与动脉僵硬度之间的关系.方法 将老年高血压脑梗死患者分为Hcy≥15μmol/L组和Hcy＜ 15μmol/L组;同时以1 400 cm/s作为临界值,分为正常组(BaPWV＜1 400 cm/s)和非正常组(BaPWV≥1 400 cm/s),测定BMI、FPG、TG、LDLC、HDLC、TC、SBP、PP、PPI、BaPWV、Hcy等指标.结果 Hcy≥15 μmol/L组SBP、PP、PPI、BaPWV均明显高于Hcy＜15 μmol/L组(P＜0.05); BaPWV非正常组SBP、PP、PPI、BaPWV明显高于正常组(P＜0.05); Hcy与SBP、PP、PPI、BaPWV正相关;BaPWV与SBP、PP、PPI、Hcy正相关.此外,Hcy与PP是脑梗死患者BaPWV升高的独立危险因素.结论 高Hcy血症是引起动脉粥样硬化、脑梗死的主要原因,Hcy水平与动脉僵硬度密切相关.
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Keywords:
- cerebral infarction /
- homocysteine /
- rial stiffness /
- correlation
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