经口内镜下肌切开术治疗贲门失弛缓症的疗效分析

郁心圃, 刘鹏飞, 包静龙

郁心圃, 刘鹏飞, 包静龙. 经口内镜下肌切开术治疗贲门失弛缓症的疗效分析[J]. 实用临床医药杂志, 2013, (17): 48-50. DOI: 10.7619/jcmp.201317015
引用本文: 郁心圃, 刘鹏飞, 包静龙. 经口内镜下肌切开术治疗贲门失弛缓症的疗效分析[J]. 实用临床医药杂志, 2013, (17): 48-50. DOI: 10.7619/jcmp.201317015
YU Xinpu, LIU Pengfei, BAO Jinglong. Analysis on therapeutic effects of peroral endoscopic myotomy in esophageal achalasia[J]. Journal of Clinical Medicine in Practice, 2013, (17): 48-50. DOI: 10.7619/jcmp.201317015
Citation: YU Xinpu, LIU Pengfei, BAO Jinglong. Analysis on therapeutic effects of peroral endoscopic myotomy in esophageal achalasia[J]. Journal of Clinical Medicine in Practice, 2013, (17): 48-50. DOI: 10.7619/jcmp.201317015

经口内镜下肌切开术治疗贲门失弛缓症的疗效分析

基金项目: 中国高校医学期刊临床专项资金
详细信息
  • 中图分类号: R573.7

Analysis on therapeutic effects of peroral endoscopic myotomy in esophageal achalasia

  • 摘要: 目的 探讨经口内镜下肌切开术治疗贲门失弛缓症的临床疗效及安全性.方法 回顾性分析本院2011年1月-2012年5月本院收治的13例贲门失弛缓症患者的临床资料,均采用经口内镜下肌切开术治疗.分析手术完成情况、食管动力学指标变化、并发症及随访情况.结果 手术成功率为100%,术后第4天所有患者均顺利进行流质饮食,吞咽困难较术前明显缓解.术后第3天患者食管下端括约肌静息压及4s完全松弛压均较术前显著降低.术中及术后均未发现气胸、发热、严重出血等患者.所有患者均获得12个月的随访,吞咽困难、呕吐及胸骨后疼痛症状消失.复查胃镜显示食管创面愈合良好,贲门口明显扩大;消化道碘油造影显示食管腔较术前显著缩小.结论 经口内镜下肌切开术可在短期内有效降低贲门失弛缓症患者食管下端括约肌静息压及括约肌4s完全松弛压,缓解吞咽困难、胸骨后疼痛等症状,且并发症发生率低,安全而有效.
  • Chuah S K, Hsu P I, Wu K L. 2011 update on esophageal achalasia [J]. World Journal of Gastroenterology, 2012, (14):1573.
    Inoue H, Minami H, Kobayashi Y. Peroral endoscopic myotomy (POEM) for esophageal achalasia [J]. Endoscopy, 2010(4):265.
    Eleftheriadis N, Inoue H, Ikeda H. Training in peroral endoscopic myotomy (POEM) for esophageal achalasia [J]. Therapeutics and Clinical Risk Management, 2012.329.
    李亮, 朱博群, 周平红. 贲门失弛缓症的内镜治疗新进展 [J]. 中华消化内镜杂志, 2011(2):116.doi: 10.3760/cma.j.issn.1007-5232.2011.02.025.
    Lee B H, Shim K Y, Hong S J. Peroral endoscopic myotomy for treatment of achalasia:initial results of a korean study [J]. Clinical Endoscopy, 2013(2):161.
    Sharata A, Kurian A A, Dunst C M. Peroral endoscopic myotomy (POEM) is safe and effective in the setting of prior endoscopic intervention [J]. Journal of Gastrointestinal Surgery, 2013(7):1188.
    令狐恩强, 李惠凯, 冯秀雪. 横开口法经口内镜下肌切开术治疗责门失弛缓症疗效及安全性评价 [J]. 中华消化内镜杂志, 2012(9):483.doi: 10.3760/cma.j.issn.1007-5232.2012.09.002.
    何利平, 郑晓玲, 梁玮. 经口内镜下肌切除术治疗贲门失弛缓症的临床疗效观察 [J]. 中华消化内镜杂志, 2012(8):449.doi: 10.3760/cma.j.issn.1007-5232.2012.08.009.
    Kolinioti A, Kayani B, Skouras C. Does laparoscopic Heller' s myotomy provide superior results compared to endoscopic dilatation for oesophageal achalasia [J]. INTERNATIONAL JOURNAL OF SURGERY, 2013(3):238.
    HungnessES, TeitelbaumEN, SantosBF. Comparison of perioperative outcomes between peroral esophageal myotomy (POEM) and laparoscopic Heller myotomy [J]. Journal of Gastrointestinal Surgery, 2013(2):228.
    内镜治疗专家协作组. 经口内镜下肌切开术治疗贲门失弛缓症专家共识 [J]. 中华胃肠外科杂志, 2012, (11):1197.doi: 10.3760/cma.j.issn.1671-0274.2012.11.026.
    Swanstrom L L, Kurian A, Dunst C M. Long-term outcomes of an endoscopic myotomy for achalasia:the POEM procedure [J]. Annals of Surgery, 2012(4):659.
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出版历程
  • 发布日期:  2013-11-26

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