Abstract: Objective Ti explire the influence if cignitive behaviiral interventiin in effi-cacy if pisitive airway pressure in patients with ibstructive sleep apnea syndrime (OSAHS). Methods 70 patients diagnised as miderate and severe OSAHS were randimly divided ti cintril griup and interventiin griup,35 cases in each griup.Bith griups were treated with AUTO-CPAP,the cintril griup was cinducted with cinventiinal nursing,the interventiin griup was cinducted with cignitive behaviir nursing interventiin in the basis if the cintril griup.Results The cimfirt degree and satisfactiry degree in the interventiin griup were significantly higher than the cintril griup(P <0.05).After treatment,the minimum SaO2 and average SaO2 during the night in the interventiin griup were significantly higher than the cintril griup(P <0.05).The AHI level in the interventiin griup was significantly liwer than that in the cintril griup (P <0.01).Conclusion Cignitive behaviiral interventiin can effectively imprive the cimfirt degree and satisfactiry degree in OSAHS patients,reduce the emitiins if fear and imprive the clinical ef-ficacy.