Effect of ozagrel combined with vinpocetine on treatment of patients with acute cerebral infarction
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摘要: 目的：观察奥扎格雷钠联合长春西汀治疗急性脑梗死的临床疗效和安全性。方法选择本院2010年10月-2013年8月住院治疗的80例急性脑梗死患者，随机分为治疗组和对照组，各40例，对照组给予常规综合治疗，治疗组在对照组治疗基础上加用奥扎格雷钠联合长春西汀静脉滴注，1次/d，2组疗程均为10 d。结果治疗组总有效率92．5％（37/40），明显优于对照组75．0％（30/40）（P ＜0．01）。2组神经功能缺损评分比较治疗组优于对照组（P ＜0．01）。2组均未见明显的不良反应。结论奥扎格雷钠联合长春西汀治疗急性脑梗死疗效确切，无不良反应，值得临床推广使用。Abstract: Objective To explore the effect and safety of ozagrel combined with vinpoce-tine in the treatment of patients with acute cerebral infarction.Methods 80 patients with acute cerebral infarction were randomly divided into treatment group and control group,40 cases in each group.Control group was treated with ozagrel and vinpocetine on the basis of control group.Re-sults The total effective rate of treatment group was 92.5% (37 /40),which was significantly higher than 75% of control group (30 /40)(P <0.01).Score of neurologic impairment in the treatment group was better than the control group (P <0.01).No obvious adverse reactions were observed in both groups.Conclusion Ozagrel combined with vinpocetine is safe and effective for treatment of acute cerebral infarction,and it causes no severe adverse reactions,so it is worthy of clinical application.
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Keywords:
- acute cerebral infarction /
- ozagrel /
- vinpocetine /
- efficacy
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