Efficacy of Xiangsha Liujunzi decoction in treatment of elderly patients with chronic gastritis and its influence on syndrome and physical sign
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摘要: 目的：探讨香砂六君子汤加减治疗老年慢性胃炎的临床效果及其对患者症状、体征的影响。方法选取老年慢性胃炎患者117例，并随机分为对照组57例和观察组60例。对照组给予西药常规抗幽门杆菌药物克拉霉素片、阿莫西林胶囊口服以及保护胃黏膜药物果胶铋胶囊治疗。观察组在对照组基础上给予香砂六君子汤为基础方加减而成的汤药治疗，1剂/d，15 d 为一个疗程。治疗6个疗程后，比较2组患者的临床症状、体征的改善情况。结果2组患者胃脘痛、胀满痞闷、嗳气、消化不良、食欲缺乏、乏力、恶心呕吐等症状均有所改善，观察组改善程度较对照组更为显著。对照组有效率为77．1％，显著低于观察组的90．0％，差异有统计学意义（P ＜0．05）。结论香砂六君子汤治疗老年慢性胃炎疗效显著，值得临床推广应用。Abstract: Objective To explore the clinical efficacy of Xiangsha Liujunzi decoction in treatment of elderly patients with chronic gastritis and its influence on syndrome and physical sign. Methods 117 elderly patients with chronic gastritis were randomly divided into control group (n=57)and observation group (n =60).The control group was treated with clarithromycin tablets, amoxicillin capsules and colloidal bismuth pectin capsules,while the observation group was treated with Xiangsha Liujunzi decoction on the basis of the control group,1 agent per day,and 15 days were counted as a course of treatment.Clinical symptoms and physical sign were compared between two groups after 6 courses of treatment.Results Clinical symptoms such as epigastric pain,ab-dominal fullness and distention,belching,dyspepsia,poor appetite,asthenia,nausea and vomiting were improved significantly in both groups.Effective rate in the control group was 77.1%,which was significantly lower than 90.0% in the observation group (P <0.05).Conclusion Xiangsha Liujunzi decoction shows a significant efficacy in treating chronic gastritis,and it is worthy of ap-plication and popularization.
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