Abstract: Objective To explore the influence of trauma score system on the traumatic re-sponse and emergency treatment efficacy of patients with severe trauma.Methods 100 patients with severe trauma were collected,and they were conducted with the injury severity score (ISS), new injury severity score (NISS),systemic inflammatory response syndrome score (SIRS),acute physiology and chronic health evaluation (APACHE Ⅱ)for evaluation of trauma after hospital ad-mission.The patients were divided into the death group (n =11)and the survival group (n =89) according to the different treatment results.Difference of trauma score was compared between the two groups.Results There were no significant differences of the age and respiratory frequency be-tween two groups (P >0.05),but the number of operation,the volume of blood transfusion,the pulse in the survival group were significantly less and lower than those in the death group,and sys-tolic blood pressure was significantly higher than that in the death group (P <0.05).ISS,NISS, SIRS,APACHE Ⅱ scores in the survival group were significantly lower than those in the death group (P <0.05).The total score of SIRS and items of SIRS were closely correlated with ISS, NISS and APACHE Ⅱ score (P <0.05).Conclusion Trauma score may reflect the severity of patients with severe trauma.