Abstract: Objective To investigate the nursing of intrathoracic anastomotic fistula after the resection of esophageal carcinoma and cardial carcinoma.Methods Nursing measures of 1109 patients undergoing intrathoracic anastomotic fistula were retrospectively analyzed.Results After active treatment and nursing,there were 15 patients recovered and 3 patients died.Conclusion Nursing measures for anastomotic fistula can effectively decrease the incidence rate of anastomotic fistula and improve the cure rate.