Abstract: 、Objective To investigate effect of behavioral therapy on medication compliance in recovery period for hospitalized psychopathic patients.Methods 312 psychopaths were random-ly divided into the control group 、147 cases、and the observation group 、154 cases、.The control group was given routine nursing intervention、and the observation group was treated with behav-ioral therapy based on routine nursing.ITAQ、PANSS、SDSS and medication compliance in the two groups were observed and compared.Results After the treatment for half a year、the medica-tion compliance rate in the observation group was 88.31% and 70.75% in the control group、the difference was significant、P <0.05、.The difference in ITAQ of two groups was statistically sig-nificant、P <0.05、、and the difference in PANSS and SDSS of two groups was not statistically sig-nificant、P >0.05、.The difference in adverse events in both groups was not statistically significant、P >0.05、.Conclusion Behavior therapy can effectively improve the medication compliance and self-management、effectively control disease recurrence、and fundamentally improve the quality of life of psychopaths.Compliance for the doctors is to prevent and cure diseases and accord to the doctors′orders、so it is worthy of promotion in clinical applications.