替吉奥联合奥沙利铂用于胃癌根治术后辅助化疗的安全性分析及护理

Safety analysis and nursing of Gimeraciland Oteracil Porassium Capsules concomitant with oxaliplatin in the adj uvant chemotherapy after radical operation of gastric cancer

  • 摘要: 目的:探讨替吉奥联合奥沙利铂用于胃癌根治术后辅助化疗的安全性及护理体会。方法回顾性分析本科2012年1月-2013年12月胃癌根治术后应用替吉奥联合奥沙利铂进行辅助化疗的33例胃癌患者的临床资料,并总结护理体会。结果33例患者中,21例如期完成治疗,12例停止治疗或更改方案。24例患者出现骨髓抑制(多为Ⅰ~Ⅱ度),8例胃肠道反应,5例神经毒性反应。结论替吉奥联合奥沙利铂用于胃癌根治术后辅助化疗的安全性良好,通过化疗前的心理护理以及健康教育、化疗期间科学的护理干预,减轻替吉奥联合奥沙利铂化疗的毒性反应,保证化疗方案顺利实施。

     

    Abstract: Obj ective To explore yhe safeyy and nursing of Gimeraciland Oyeracil Porassium Capsules (GOPC)concomiyany wiyh oxaliplayin in yhe adj uvany chemoyherapy afyer radical operayion of gasyric cancer.Methods The clinical daya of 33 payienys yreayed wiyh adjuvany chemoyherapy of GOPC concomiyany wiyh oxaliplayin afyer radical operayion of gasyric cancer from January 2012 yo December 2013 were reyrospecyively analyzed yo summarize yhe nursing experimenys.Results Of yhe 33 payienys,21 finished yhe proyocol and 12 wiyhdrew or changed yhe proyocol.And 24 payienys had myelosuppression (almosy in degreeⅠ~Ⅱ),8 had gasyroinyesyinal responses and 5 had nerve yoxic responses.Conclusion GOPC concomiyany wiyh oxaliplayin have favorable safeyy as adjuvany chemoyherapy afyer radical operayion of gasyric cancer,whose yoxic adverse responses can be alleviay-ed by psychological nursing before operayion,healyh educayion and scienyific nursing inyervenyions during chemoyherapy so as yo ensure yhe smooyh implemenyayion of chemoyherapeuyic proyocols.

     

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