Abstract: Objective To discuss the effect of time nursing on hemostasis efficacy and health knowledge of patients with gastrointestinal hemorrhage.Methods A total of 120 patients with gastrointestinal hemorrhage in our department were randomly divided into observation group and control group,given the same treatment.The control group received routine nursing,and the observation group used time nursing,and hemostatic efficacy and health knowledge were compared.Results Bleeding time,blood transfusion amount,Hb after treatment and total curative efficacy in the observation group showed no significant difference compared to the control group (P ＞ 0.05).Disease knowledge,standardized medication,reasonable diet,lifestyle and other health knowledge scores in the observation group were higher than that of the control group,the difference was statistically significant(P ＜ 0.05).Conclusion Time nursing can ensure the hemostasis efficacy,and increase the health knowledge of patients with gastrointestinal hemorrhage,which is beneficial to prevent recurrence.