Abstract: Objective To investigate the effect of nursing intervention on quality of life of lumbar disc herniation patients with conservative treatment.Methods A total of 120 lumbar disc herniation cases treated by conservative treatment in our hospital were randomly divided into observation group and control group,with 60 cases in each group.The control group received routine nursing while observation group strengthened physical and psychological rehabilitation nursing.Pain,lumbar function and quality of life before and after treatment between the two groups were compared.Results After nursing,the observation group had lower pain score,flexion and extension,lateral flexion and rotation activity were larger than the control group,the differences were statistically significant (P ＜ 0.05).After nursing,bodily pain,social function,mental function,activity and other aspects of quality of life in the observation group were higher than the control group,the difference was statistically significant (P ＜ 0.05).Conclusion Strengthening nursing intervention can improve the effect of conservative treatment,and improve the quality of life of patients with lumbar disc herniation.