Abstract: Objective To analyze and study the relationship between erythrocyte immune,cellular immune and Hp infection in patients with gastric ulcer.Methods A total of 76 patients with gastric ulcer were selected as the observation group,and 76 healthy people at the same period were selected as the control group.The erythrocyte immune and cellular immune indexes of two groups were detected,and the relationship between erythrocyte immune,cellular immune and Hp infection in patients with gastric ulcer were analyzed by the Logistic analysis.Results The erythrocyte immune and cellular immune indexes of observation group were significantly worse than those of control group,and the erythrocyte immune and cellular immune indexes of observation group with Hp infection were significantly worse than those of patients without Hp infection,and the detection results of patients with higher DOB value of Hp infection were significantly worse than those of patients with lower DOB value of Hp infection,and the erythrocyte immune and cellular immune indexes had close relationship with the Hp infection in patients with gastric ulcer (P ＜ 0.05).Conclusion The erythrocyte immune and cellular immune of patients with gastric ulcer and Hp infection show worse state,and the influence of Hp infection degree for the expression state of immune indexes are greater,so they should be given targeted regulatory intervention.