川芎嗪注射液对肺结核肺功能及纤维化状态的影响

阳艳

阳艳. 川芎嗪注射液对肺结核肺功能及纤维化状态的影响[J]. 实用临床医药杂志, 2017, (5): 39-41. DOI: 10.7619/jcmp.201705011
引用本文: 阳艳. 川芎嗪注射液对肺结核肺功能及纤维化状态的影响[J]. 实用临床医药杂志, 2017, (5): 39-41. DOI: 10.7619/jcmp.201705011
YANG Yan. Influence of ligustrazine injection on pulmonary function and fibrosis state of patients with pulmonary tuberculosis[J]. Journal of Clinical Medicine in Practice, 2017, (5): 39-41. DOI: 10.7619/jcmp.201705011
Citation: YANG Yan. Influence of ligustrazine injection on pulmonary function and fibrosis state of patients with pulmonary tuberculosis[J]. Journal of Clinical Medicine in Practice, 2017, (5): 39-41. DOI: 10.7619/jcmp.201705011

川芎嗪注射液对肺结核肺功能及纤维化状态的影响

基金项目: 湖北省自然科学基金项目。
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  • 中图分类号: R521

Influence of ligustrazine injection on pulmonary function and fibrosis state of patients with pulmonary tuberculosis

  • 摘要: 目的 研究川芎嗪注射液对肺结核肺功能及纤维化状态的影响.方法 选取本院诊治的62例肺结核患者为研究对象,将62例患者随机分为对照组和观察组,每组各31例.对照组进行常规肺结核治疗,观察组则在对照组常规治疗的基础上加用川芎嗪注射液进行治疗,比较2组患者治疗前后的肺功能(肺通气和肺换气功能指标)及纤维化状态指标.结果 治疗前,2组患者的肺通气和肺换气功能指标、纤维化状态指标比较,差异无统计学意义(P>0.05);治疗后,观察组的肺通气和肺换气功能指标均好于对照组,纤维化状态相关血清指标均低于对照组,差异均有统计学意义(P<0.05).结论 川芎嗪注射液可明显改善肺结核患者的肺功能及纤维化状态,对于肺结核的治疗应用价值相对较高.
    Abstract: Objective To study the influence state of ligustrazine injection on pulmonary function and fibrosis state of patients with pulmonary tuberculosis.Methods A total of 62 patients with pulmonary tuberculosis in our hospital were randomly divided into control group and observation group with 31 cases per group,the control group were treated with conventional treatment of pulmonary tuberculosis,the observation group were treated with ligustrazine injection based on the conventional treatment,then the pulmonary function(pulmonary ventilation and transition function indexes)and fibrosis state indexes of two groups before and after the treatment were analyzed and compared.Results The pulmonary ventilation and transition function indexes,fibrosis state indexes of two groups before the treatment were compared (P > 0.05),while the pulmonary ventilation and transition function indexes of observation group after the treatment were all better than that of control group,the fibrosis state related serum indexes were all lower than that of control group(P < 0.05).Conclusion The ligustrazine injection can obviously improve the pulmonary function and fibrosis state of patients with pulmonary tuberculosis,so it's worthy of application in the treatment of pulmonary tuberculosis.
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