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男性幽门螺旋杆菌感染与骨质相关关系研究

Correlation between Helicobacter pylori infection and bone in men

    摘要
  • 摘要:
      目的  了解目前沈阳地区男性幽门螺旋杆菌感染情况及骨质相关指标，并分析其相关性。
      方法  收集本体检中心检测幽门螺旋杆菌，同时检测骨密度检测及维生素D、碱性磷酸酶等相关指标的人群的临床资料。将研究对象分为幽门螺旋杆菌阴性组和幽门螺旋杆菌阳性组，分析幽门螺旋杆菌感染和骨密度检测及维生素D、碱性磷酸酶等相关指标的相关关系。
      结果  443例男性检测幽门螺旋杆菌者中，阳性检出率为32.05%。2组骨密度、维生素D比较，差异有统计学意义(P < 0.05); 2组碱性磷酸酶比较差异无统计学意义(P>0.05)。
      结论  幽门螺旋杆菌阳性感染可能与骨密度及维生素D有关，而不能认为与碱性磷酸酶之间存在关系。

     

    Abstract:
      Objective  To investigate the status of Helicobacter pylori infection and bone-related indicators in men and their correlation.
      Methods  A data of patients performed examination of Helicobacter pylori, and bone related indexes such as vitamin D and alkaline phosphatase in our physical examination center were retrospectively analyzed. The subjects were divided into Helicobacter pylori-negative group and Helicobacter pylori-positive group. The correlation between Hp infection and bone mineral density, vitamin D, alkaline phosphatase were analyzed.
      Results  Out of 443 males tested for Helicobacter pylori, the positive detection rate was 32.05%. There were significant differences in bone mineral density and vitamin D between the two groups (P < 0.05), but no significant difference in alkaline phosphatase (P>0.05).
      Conclusion  The Hp infection may be related to bone density and vitamin D, but it can not be considered to be related to alkaline phosphatase.

     

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