Abstract:
Objective To investigate the relationship between intima-media thickness(IMT), stenosis severity and carotid atherosclerosis in patients with calcification of cardiac valve by cardiac color Doppler ultrasound.
Methods A total of 90 patients with senile calcific valve heart disease (SCVHD) and coronary atherosclerosis(CAS) were enrolled in the study group were selected as study group. In the same period, 60 patients with CAS alone without SCVHD were as control group, and 60 patients with non-cardiovascular disease were included as the healthy group. The valve thickness, IMT, and stenosis were compared between the three groups, and the correlation between MT, stenosis and valve thickness was analyzed. Logistic multiple regression analysis was used to analyze its relationship with valve thickness.
Results There were significant differences in valve thickness, IMT, and stenosis in the three groups (P < 0.01). The indexes of the control group were significantly higher than the healthy group (P < 0.01), and the study group weresignificantly higher than that of the control group and the healthy group (P < 0.01). There was a positive correlation between IMT, stenosis and valve thickness (P < 0.01). The IMT and stenosis degree of CAS patients were risk factors for SCVHD (P < 0.01).
Conclusion SCVHD combined with CAS patients had higher IMT and stenosis severity, which can be used as an independent factor for SCVHD patients with CAS.
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