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药物涂层球囊治疗下肢动脉粥样硬化闭塞性疾病的疗效评价

Efficacy evaluation of drug-coated balloon therapy in treating patients with atherosclerotic occlusive disease of lower extremity

    摘要
  • 摘要:
      目的  探讨药物涂层球囊治疗下肢动脉粥样硬化闭塞性疾病的疗效。
      方法  回顾性分析接受药物涂层球囊治疗的38例下肢动脉硬化闭塞性疾病患者的术前、术中以及术后随访资料。
      结果  本研究38例患者患肢血管均再通成功，术后随访期间均未发生与手术相关或其他原因导致的死亡、截肢、靶病变血栓形成等并发症，无需要手术再干预患者，随访率100.00%。术后6个月、1年的Ⅰ期通畅率为84.21%、73.68%。所有患者术后不同时点的踝肱指数(ABI)、行走距离、Rutherford分级均较术前显著改善(P < 0.05)。
      结论  药物涂层球囊治疗下肢动脉粥样硬化闭塞性疾病的疗效显著。

     

    Abstract:
      Objective  To explore the efficacy of drug-coated balloon therapy in treatment of patients with atherosclerotic occlusive disease of lower extremity.
      Methods  The preoperative, intra-operative and postoperative follow-up data of 38 patients with arteriosclerosis occlusive disease of lower extremity treated by drug-coated balloon therapy were retrospectively analyzed.
      Results  All the 38 patients had successful revascularization of affected limbs. During the follow-up period, no complications such as death, amputation, thrombosis of target lesions and other complications associated with surgery occurred. No patients with further intervention were observed, and the follow-up rate was 100.00%. The patency rate of stage Ⅰ was 84.21% and 73.68% at 6 months and 1 year after operation. Ankle Brachial Index (ABI), walking distance and Rutherford grading of all patients at different time points after operation were significantly improved when compared with those before operation (P < 0.05).
      Conclusion  Drug-coated balloon therapy is effective in the treatment of patients with atherosclerotic occlusive diseases of lower extremity.

     

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