Objective  To investigate the effect of laparoscopic salpingectomy combined with uterine horn suture for patients with tubal pregnancy.

  Methods  A total of 100 patients with tubal pregnancy were randomly divided into 2 groups, the control group(n=50) underwent laparoscopic preservation of tubal pregnancy lesions, and 50 patients in the observation group underwent laparoscopic tubal core-pulling resection combined with uterine horn suture. Operation time, intraoperative blood loss, hospital stay, decrease situation of postoperative blood human chorionic gonadotropin (HCG), intrauterine pregnancy, ectopic pregnancy, ovarian function of two groups were compared.

  Results  There was no significant difference in operation time and hospital stay between the control group and the observation group (P>0.05), and the blood loss in the control group was significantly more than that in the observation group (P < 0.05). Compared with the control group, the blood HCG level in the observation group decreased more significantly (P < 0.05). At 1, 3 and 6 months after treatment, there were no significant differences in serum luteinizing hormone (LH), follicle-stimulating hormone (FSH), AMH and estradiol (E₂) levels between the two groups (P>0.05). After 18 months of follow-up, the incidence of ectopic pregnancy in the observation group was lower than that in the control group (4.00% vs. 12.00%), and there was no significant difference in intrauterine pregnancy rate between the two groups.

  Conclusion  Laparoscopic salpingectomy combined with cornual suture can effectively reduce the incidence of second ectopic pregnancy and has no effect on ovarian function.