Objective  To investigate the effect of oral administration of contraceptives on prevention of recurrence after hysteroscopic endometrial polypectomy.

  Methods  A total of 240 patients with endometrial polyps (EP) were randomly divided into control group (n=120) and observation group (n=120). The control group was treated with hysteroscopic endometrial polypectomy alone, and the observation group was treated with compound short-acting contraceptives after operation. The changes of hemoglobin (Hb) and endometrial thickness were observed at 3 and 6 months after operation, and menstrual improvement and EP recurrence were compared between the two groups.

  Results  The serum Hb level increased significantly, and the endometrial thickness decreased significantly at 3 and 6 months after operation (P < 0.05), and the observation group changes more significantly at 6 months after operation than the control group(P < 0.05). The rate of returning to regular menstruation at 6 months after operation in the observation group was higher, and the recurrence rate of EP was lower than that in the control group(91.67% vs. 78.33%, 4.17%vs. 14.17, P < 0.05).

  Conclusion  Oral administration of short-acting contraceptives after hysteroscopic endometrial polypectomy can increase the level of serum Hb and inhibit endometrial hyperplasia, and play a positive role in improving menstruation and prevention of EP recurrence.