过氧化物酶体增殖物激活受体γ与妊娠期糖尿病相关性

刘可琢; 王慧艳

doi:10.7619/jcmp.201919034

过氧化物酶体增殖物激活受体γ与妊娠期糖尿病相关性

南京医科大学附属常州妇幼保健院产科, 江苏常州, 213003

基金项目:

江苏省常州市科技局应用基础研究项目 CJ20159055

详细信息

通讯作者:
王慧艳, E-mail: huiyanwang@njmu. edu.cn

中图分类号: R587.1
计量
- 文章访问数: 0113
- HTML全文浏览量: 064
- PDF下载量: 01
出版历程
- 收稿日期: 2019-08-05
- 录用日期: 2019-09-11
- 网络出版日期: 2021-02-28
- 发布日期: 2019-10-14

Relationship between peroxisome proliferator-activated receptor γ and gestational diabetes mellitus

摘要

- 过氧化物酶体增殖物激活受体γ /
- 妊娠期糖尿病 /
- 胰岛素抵抗 /
- 脂类代谢

HTML全文

参考文献(37)

[1]	李佳, 陈必良.胰岛素抵抗对妊娠期糖尿病影响的研究进展[J].中国妇幼健康研究, 2009, 20(6): 718-720. doi: 10.3969/j.issn.1673-5293.2009.06.043
[2]	胡玲, 王程琳, 郑文霞, 等.妊娠糖尿病患者脂肪因子炎症因子与胰岛素抵抗的关系[J].中国药物与临床, 2015, 15(6): 825-827. https://www.cnki.com.cn/Article/CJFDTOTAL-YWLC201506039.htm
[3]	叶爱玲, 颜勤明, 柴泽音, 等.妊娠期糖尿病视黄醇结合蛋白4与炎症因子、胰岛素抵抗相关分析[J].中国医师杂志, 2011(4): 480-483. doi: 10.3760/cma.j.issn.1008-1372.2011.04.015
[4]	Mørkrid K, Jenum A K, Sletner L, et al. Failure to increase insulin secretory capacity during pregnancy-induced insulin resistance is associated with ethnicity and gestational diabetes[J]. Eur J Endocrinol, 2012, 167(4): 579-588. doi: 10.1530/EJE-12-0452
[5]	Galic S, Oakhill J S, Steinberg G R. Adipose tissue as an endocrine organ[J]. Mol Cell Endocrinol, 2010, 316(2): 129-139. doi: 10.1016/j.mce.2009.08.018
[6]	杨谷良, 潘敏雄, 向福, 等. PPARγ调控脂肪细胞增殖和分化机理研究进展[J].食品科学, 2017, 38(3): 254-260. https://www.cnki.com.cn/Article/CJFDTOTAL-SPKX201703047.htm
[7]	Takada I, Makishima M. PPARγ ligands and their therapeutic applications: a patent review (2008-2014)[J]. Expert Opin Ther Pat, 2015, 25(2): 175-191. doi: 10.1517/13543776.2014.985206
[8]	Glass C K, Ogawa S. Combinatorial roles of nuclear receptors in inflammation and immunity[J]. Nat Rev Immunol, 2006, 6(1): 44-55. doi: 10.1038/nri1748
[9]	Taxvig C, Dreisig K, Boberg J, et al. Differential effects of environmental chemicals and food contaminants on adipogenesis, biomarker release and PPARγ activation[J]. Mol Cell Endocrinol, 2012, 361(1/2): 106-115.
[10]	Tenenbaum A, Fisman E Z. Balanced pan-PPAR activator bezafibrate in combination with statin: comprehensive lipids control and diabetes prevention[J]. Cardiovasc Diabetol, 2012, 11: 140. doi: 10.1186/1475-2840-11-140
[11]	Gross B, Staels B. PPAR agonists: multimodal drugs for the treatment of type-2 diabetes[J]. Best Pract Res Clin Endocrinol Metab, 2007, 21(4): 687-710. doi: 10.1016/j.beem.2007.09.004
[12]	Yadav A, Kataria M A, Saini V, et al. Role of leptin and adiponectin in insulin resistance[J]. Clin Chim Acta, 2013, 417: 80-84. doi: 10.1016/j.cca.2012.12.007
[13]	Pickup J C. Inflammation and activated innate immunity in the pathogenesis of type 2 diabetes[J]. Diabetes Care, 2004, 27(3): 813-823. doi: 10.2337/diacare.27.3.813
[14]	Black M H, Wu J, Takayanagi M, et al. Variation in PPARG is associated with longitudinal change in insulin resistance in Mexican Americans at risk for type 2 diabetes[J]. J Clin Endocrinol Metab, 2015, 100(3): 1187-1195. doi: 10.1210/jc.2014-3246
[15]	李吉隆, 周杰, 王宝利. microRNA-200c对3T3-L1前体脂肪细胞向脂肪细胞分化的调控作用[J].国际内分泌代谢杂志, 2017, 3(37): 2-2.
[16]	谢军, 韩造木. MiRNA-27a通过PPARγ介导3T3-L1细胞胰岛素抵抗[J].华南国防医学杂志, 2017, 31(5): 293-296. https://www.cnki.com.cn/Article/CJFDTOTAL-HNGY201705003.htm
[17]	谢军, 蔡克银. MiRNA-27a对3T3-L1细胞胰岛素抵抗的作用及机制[J].华南国防医学杂志, 2014, 28(2): 97-99, 112. https://www.cnki.com.cn/Article/CJFDTOTAL-HNGY201402003.htm
[18]	Capobianco E, White V, Higa R, et al. Effects of natural ligands of PPARgamma on lipid metabolism in placental tissues from healthy and diabetic rats[J]. Mol Hum Reprod, 2008, 14(8): 491-499. doi: 10.1093/molehr/gan039
[19]	潘小佳, 高宇, 朱智鹏. PPARγ在妊娠期糖尿病脂肪及胎盘组织的表达及临床意义[J].中国医学工程, 2015, 23(7): 165, 167. https://www.cnki.com.cn/Article/CJFDTOTAL-YCGC201507121.htm
[20]	李珍, 赖光锐, 宋薇薇. PPARγ在妊娠期糖尿病脂肪及胎盘组织的表达研究[J].国际遗传学杂志, 2014, 37(6): 278-303. doi: 10.3760/cma.j.issn.1673-4386.2014.06.002
[21]	Márkus B, Vörös K, Supák D, et al. Association of PPAR alpha intron 7 G/C, PPAR gamma 2 Pro12Ala, and C161T polymorphisms with serum fetuin-A concentrations[J]. PPAR Res, 2017, 2017: 7636019. http://europepmc.org/abstract/MED/28781590
[22]	Tok E C, Ertunc D, Bilgin O, et al. PPAR-gamma2 Pro12Ala polymorphism is associated with weight gain in women with gestational diabetes mellitus[J]. Eur J Obstet Gynecol Reprod Biol, 2006, 129(1): 25-30. doi: 10.1016/j.ejogrb.2006.03.016
[23]	Dong C P, He L, Li J N, et al. Association of the Pro12Ala and C1431T polymorphism of the PPAR gamma2 gene and their haplotypes with obesity and type 2 diabetes[J]. Chin J Med Genet, 2008, 25(4): 447-451. http://www.ncbi.nlm.nih.gov/pubmed/18683148/
[24]	Wang L H, Xu W T, Wang X. Peroxisome proliferator-activated receptor Pro12Ala polymorphism and the risks of gestational diabetes mellitus: An updated meta-analysis of 12 studies[J]. Medicine (Baltimore), 2016, 95(44): e5090. doi: 10.1097/MD.0000000000005090
[25]	张展, 蒋陈东, 冯杨, 等.过氧化物酶体增殖物激活受体γ2基因Pro12Ala多态性与妊娠期糖尿病的关系Meta分析[J].中华围产医学杂志, 2016, 19(4): 308-314. doi: 10.3760/cma.j.issn.1007-9408.2016.04.015
[26]	郭乌兰, 唐勇, 韩学尧, 等.中国汉族人群过氧化物酶体增殖物激活受体γ基因Pro12Ala多态性与2型糖尿病相关性的Meta分析[J].中国医学科学院学报, 2011, 33(6): 593-599. doi: 10.3881/j.issn.1000-503X.2011.06.002
[27]	程琰, 马瑶, 彭婷, 等.孕妇及其子代PPAR γ2基因型差异与妊娠期糖尿病发病的关系[J].中华妇产科杂志, 2010, 45(3): 170-173. https://cdmd.cnki.com.cn/Article/CDMD-10114-1020751107.htm
[28]	刘文惠, 杨晓红, 张元珍. PPAR-γ基因多态性与妊娠期糖尿病相关性的初步探讨[J].武汉大学学报:医学版, 2014, 35(1): 69-73 https://www.cnki.com.cn/Article/CJFDTOTAL-HBYK201401015.htm
[29]	Wang H Y, Jiang H Y, Yang L P, et al. Impacts of dietary fat changes on pregnant women with gestational diabetes mellitus: a randomized controlled study[J]. Asia Pac J Clin Nutr, 2015, 24(1): 58-64. http://europepmc.org/abstract/med/25740743
[30]	Ryckman K K, Spracklen C N, Smith C J, et al. Maternal lipid levels during pregnancy and gestational diabetes: a systematic review and meta-analysis[J]. BJOG, 2015, 122(5): 643-651. doi: 10.1111/1471-0528.13261
[31]	Leng J H, Shao P, Zhang C P, et al. Prevalence of gestational diabetes mellitus and its risk factors in Chinese pregnant women: a prospective population-based study in Tianjin, China[J]. PLoS One, 2015, 10(3): e0121029. http://www.ncbi.nlm.nih.gov/pubmed/25799433
[32]	Chon S J, Kim S Y, Cho N R, et al. Association of variants in PPARγ2, IGF2BP2, and KCNQ1 with a susceptibility to gestational diabetes mellitus in a Korean population[J]. Yonsei Med J, 2013, 54(2): 352-357. doi: 10.3349/ymj.2013.54.2.352
[33]	Papi A, De Carolis S, Bertoni S, et al. PPARγ and RXR ligands disrupt the inflammatory cross-talk in the hypoxic breast cancer stem cells niche[J]. J Cell Physiol, 2014, 229(11): 1595-1606. doi: 10.1002/jcp.24601
[34]	Hallenborg P, Petersen R K, Kouskoumvekaki I, et al. The elusive endogenous adipogenic PPARγ agonists: Lining up the suspects[J]. Prog Lipid Res, 2016, 61: 149-162. doi: 10.1016/j.plipres.2015.11.002
[35]	Dalla Nora E, Gray S L, Vidal-Puig A J. Mouse models of PPAR-γ deficiency: dissecting PPAR-γ′s role in metabolic homoeostasis[J]. Biochem Soc Trans, 2005, 33(5): 1053. doi: 10.1042/BST0331053
[36]	Chistiakov D A. The peroxisomal proliferator-activated receptor gamma isoform 2 (PPARgamma2) is an established susceptibility marker for type 2 diabetes (T2D)[J]. Autoimmunity, 2008, 41(5): 338-339. doi: 10.1080/08916930802011183
[37]	Wang S B, Dougherty E J, Danner R L. PPARγ signaling and emerging opportunities for improved therapeutics[J]. Pharmacol Res, 2016, 111: 76-85. doi: 10.1016/j.phrs.2016.02.028

施引文献(3)

期刊类型引用(2)

1.	何方，翁英，许洁颖. 老年阿尔茨海默病住院患者营养风险发生状况及其影响因素. 中国老年学杂志. 2023(01): 74-76 . 百度学术
2.	陈丽琴. MISA评估对高龄患者营养和压力性损伤的影响. 中国继续医学教育. 2019(18): 138-141 . 百度学术

其他类型引用(1)

资源附件(0)

计量

文章访问数:
HTML全文浏览量:
PDF下载量:
被引次数: 3

过氧化物酶体增殖物激活受体γ与妊娠期糖尿病相关性

通讯作者: 王慧艳, E-mail: huiyanwang@njmu. edu.cn

计量

出版历程

Relationship between peroxisome proliferator-activated receptor γ and gestational diabetes mellitus

期刊类型引用(2)

其他类型引用(1)

计量

出版历程

目录

通讯作者:
王慧艳, E-mail: huiyanwang@njmu. edu.cn