Objective  To analyze the related factors and preventive measures of neonatal persistent pulmonary hypertension (PPHN) after resuscitation for neonatal asphyxia.

  Methods  Totally 50 neonates with neonatal asphyxia were selected and divided into two groups. Pulmonary hypertension group included 16 cases with the difference of partial pressure of oxygenp(O₂) between anterior (right radial artery) and posterior (left radial artery) over 15 mmHg, and non-pulmonary hypertension group included 34 cases with the difference of p(O₂) less than or equal to 15 mmHg. The 20 cases with p(O₂) difference from 5 to 15 mmHg in non-pulmonary hypertension group were randomly divided into conventional treatment group (n=10) and intervention group (n=10). Related factors of neonatal persistent pulmonary hypertension after resuscitation for neonatal asphyxia were analyzed, and the total effective rate between conventional group and intervention group was compared.

  Results  Age, birth weight, blood sugar, blood pressure, body temperature, resuscitation rescue methods and pH value of blood gas were the influencing factors of neonatal persistent pulmonary hypertension after resuscitation for asphyxia (P < 0.05). The total effective rate of intervention group was significantly higher than that of conventional group (P < 0.05).

  Conclusion  There are many factors related to neonatal persistent pulmonary hypertension after resuscitation for neonatal asphyxia, including age, birth weight, blood sugar, blood pressure, body temperature, average pH value of blood gas, resuscitation and rescue methods. According to the related factors of PPHN, the incidence rate of PPHN can be effectively reduced by giving specific preventive measures to children with PPHN.