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乌头汤治疗风湿性多肌痛的临床疗效分析

Clinical effect of Wutou Decoction on polymyalgia rheymatica

    摘要
  • 摘要:
      目的  探讨乌头汤治疗风湿性多肌痛(PMR)的临床疗效。
      方法  选择PMR患者160例分为观察组与对照组，各80例。对照组给予强的松治疗，观察组在对照组治疗基础上加用乌头汤治疗，比较2组患者治疗效果、C反应蛋白(CRP)、血沉(ESR)、血红蛋白(HGB)、血小板(PLT)水平变化。同时，观察晨僵消失时间、ESR恢复至0~20 mm/h的时间、CRP恢复正常值时间。
      结果  观察组患者治疗有效率高于对照组，差异有统计学意义(P < 0.05); 2组治疗后CRP、ESR、PLT水平均低于治疗前(P < 0.05); 治疗后, 2组HGB高于治疗前，差异有统计学意义(P < 0.05); 治疗后，观察组CRP、ESR、PLT水平显著低于对照组，HGB水平显著高于对照组，差异有统计学意义(P < 0.05); 观察组患者晨僵消失时间、ESR恢复至0~20 mm/h时间、CRP恢复正常值时间短于对照组，差异有统计学意义(P < 0.05)。
      结论  乌头汤联合强的松治疗PMR具有显著疗效，可有效改善患者临床症状。

     

    Abstract:
      Objective  To discuss the effect of Wutou Decoction on polymyalgia rheymatica.
      Methods  A total of 160 patients with polymyalgia rheymatica were divided into observation group(n=80) and control group(n=80), the controlgroup was treated with prednisone, the observation group was treated with Wutou Decoction on the basis of the control group. The therapeutic effects, changes of C reactive protein (CRP), erythrocyte sedimentation rate(ESR), hemoglobin(HGB) and blood platelet(PLT) levels were compared. The disappearance time of stiffness in the morning, recovery time of ESR to 0~20 mm/h and recovery time of CRP to normal value were compared between the two groups.
      Results  The effective rate of treatment in the observation group was significantly higher than the control group (P < 0.05); the CRP, ESR and PLT levels in the two groups after treatment were significantly lower, and HGB level was significantly higher than treatment before(P < 0.05). After treatment, the levels of CRP, ESR and PLT in the observation group were significantly lower, and HGB levels were significantly higher than those in the control group (P < 0.05); the observation group had lower disappearance time of stiffness in the morning, recovery time of ESR to 0~20 mm/h and recovery time of CRP to normal value than that in the control group (P < 0.05).
      Conclusion  ERCP combined with EST has higher efficacy in the treatment of patients with PMR, and improve the clinical efficacy.

     

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