硬膜外腔前侧间隙置管连续阻滞联合腰椎低温等离子消融术治疗椎间盘源性腰痛的效果观察

王静, 张晓丹, 张淼, 张军强

王静, 张晓丹, 张淼, 张军强. 硬膜外腔前侧间隙置管连续阻滞联合腰椎低温等离子消融术治疗椎间盘源性腰痛的效果观察[J]. 实用临床医药杂志, 2020, 24(5): 36-39. DOI: 10.7619/jcmp.202005010
引用本文: 王静, 张晓丹, 张淼, 张军强. 硬膜外腔前侧间隙置管连续阻滞联合腰椎低温等离子消融术治疗椎间盘源性腰痛的效果观察[J]. 实用临床医药杂志, 2020, 24(5): 36-39. DOI: 10.7619/jcmp.202005010
WANG Jing, ZHANG Xiaodan, ZHANG Miao, ZHANG Junqiang. Effect observation of continuous block with catheterization in the anterior space of epidural space combined with lumbar low temperature plasma ablation in treatment of patients with discogenic low back pain[J]. Journal of Clinical Medicine in Practice, 2020, 24(5): 36-39. DOI: 10.7619/jcmp.202005010
Citation: WANG Jing, ZHANG Xiaodan, ZHANG Miao, ZHANG Junqiang. Effect observation of continuous block with catheterization in the anterior space of epidural space combined with lumbar low temperature plasma ablation in treatment of patients with discogenic low back pain[J]. Journal of Clinical Medicine in Practice, 2020, 24(5): 36-39. DOI: 10.7619/jcmp.202005010

硬膜外腔前侧间隙置管连续阻滞联合腰椎低温等离子消融术治疗椎间盘源性腰痛的效果观察

详细信息
  • 中图分类号: R681.5

Effect observation of continuous block with catheterization in the anterior space of epidural space combined with lumbar low temperature plasma ablation in treatment of patients with discogenic low back pain

  • 摘要: 目的 探讨硬膜外腔前侧间隙置管连续阻滞联合腰椎低温等离子消融术治疗椎间盘源性腰痛的临床效果。 方法 选取椎间盘源性腰痛患者106例,根据治疗方案分为2组各53例。对照组给予硬膜外腔前侧间隙置管连续阻滞治疗,观察组给予硬膜外腔前侧间隙置管连续阻滞联合腰椎低温等离子消融术治疗。比较2组不同时点数字分级法(NRS)评分(术前、术后1周、术后1个月、术后3个月)、改良Macnab评定结果(术后1、3个月)、改良日本骨科学会腰痛功能评价表(M-JOA)评分(术前、术后1个月、术后3个月)以及血清白介素-1(IL-1)与白介素-6(IL-6)水平(术前、术后1个月、术后3个月)。 结果 2组术前及术后1周NRS评分比较无显著差异(P>0.05); 术后1、3个月,观察组NRS评分显著低于对照组(P<0.05)。术后1、3个月,观察组Macnab评定优良率显著高于对照组(P<0.05)。术后1、3个月,观察组M-JOA评分显著高于对照组(P<0.05)。观察组术后1个月血清IL-1、IL-6水平显著低于对照组(P<0.05)。 结论 硬膜外腔前侧间隙置管连续阻滞联合腰椎低温等离子消融术治疗椎间盘源性腰痛患者安全、有效,可降低血清IL-1、IL-6水平。
    Abstract: Objective To investigate the clinical effect of continuous block with catheterization in the anterior space of epidural space combined with lumbar low temperature plasma ablation in treatment of patients with discogenic low back pain. Methods A total of 106 patients with discogenic low back pain were selected and divided into two groups according to the treatment plan. The control group was treated with continuous block with catheterization in the anterior space of epidural space, while the observation group was treated with continuous block with catheterization in the anterior space of epidural space combined with lumbar low temperature plasma ablation. The NRS scores(before operation, 1 week after operation, 1 month after operation, 3 months after operation), the modified Macnab scores(before operation, 1 month after operation, 3 months after operation), the M-JOA scores(before operation, 1 month after operation, 3 months after operation)and the levels of interleukin-1(IL-1)and interleukin-6(IL-6)(before operation, 1 month after operation, 3 months after operation)were compared between the two groups. Results There were no significant difference in NRS scores between the two groups before operation and 1 week after operation(P>0.05). The NRS scores of the observation group were significantly lower than those of the control group at 1 and 3 months after operation(P<0.05). The excellent and good rates of Macnab in the observation group - were significantly higher than those in the control group at 1 and 3 months after operation(P<0.05). At 1 and 3 months after operation, the M-JOA scores of the observation group were significantly higher than those of the control group(P<0.05). The serum levels of IL-1 and IL-6 in the observation group were significantly lower than those in the control group(P<0.05). Conclusion Continuous block with catheterization in the anterior space of epidural space combined with lumbar low temperature plasma ablation is effective and safe in treatment of patients with discogenic low back pain, which can reduce serum IL-1 and IL-6 levels.
  • Saqib M, Bhatti S N, Khan M A, et al. Outcome analysis of two different injection solutions for epidural injection in radicular lumbar backache syndromes[J]. J Ayub Med Coll Abbottabad, 2016, 28(4): 709-714.

    曹春风, 王群波, 卢旻鹏, 等. 椎间盘源性腰痛的诊断和治疗进展[J]. 颈腰痛杂志, 2016, 37(2): 143-146.
    王永铭. 疏肝补肾汤配合运动疗法治疗椎间盘源性腰痛疗效及对生存质量的影响[J]. 现代中西医结合杂志, 2016, 25(22): 2414-2417.
    吴迪, 黄岩石, 郑铁牛, 等. PTED和低温等离子射频治疗椎间盘源性腰痛临床研究[J]. 临床心身疾病杂志, 2018, 24(1): 64-66

    , 83.

    吴照鹏, 马航. 低温等离子靶点消融术联合臭氧治疗盘源性腰痛的临床效果[J]. 临床医学研究与实践, 2019(9): 73-75.
    程秋平, 刘晓瑜, 谢慰, 等. 温针灸结合体位调整护理法治疗椎间盘源性下腰痛临床观察[J]. 中国中医急症, 2016, 25(9): 1749-1752.
    范少勇, 胡梁深, 周明. 中药熏蒸联合洪都督脉经手法治疗椎间盘源性腰痛疗效观察[J]. 广州中医药大学学报, 2019, 36(6): 824-826.
    郭玉娜, 窦智, 李小琳, 等. 低温等离子消融术联合硬膜外置管治疗盘源性腰痛的效果[J]. 中国医药导报, 2018, 15(28): 111-114.
    左明明, 陈雪飘, 刘金锋. 硬膜外腔药物注射治疗腰椎间盘突出症的研究进展[J]. 中国疼痛医学杂志, 2017, 23(4): 299-302.

    Navone S E, Marfia G, Giannoni A, et al. Inflammatory mediators and signalling pathways controlling intervertebral disc degeneration[J]. Histol Histopathol, 2017, 32(6): 523-542.

    芦海燕, 杨立强, 唐元章, 等. 腰椎间盘低温等离子消融联合腰交感神经导管置入治疗盘源性内脏痛的效果[J]. 中国医药导报, 2018, 15(28): 99-102.
    云晨, 韩广, 蒋显锋, 等. 射频消融治疗脊柱内镜术后椎间盘源性脊神经后支疼痛的疗效分析[J]. 中国中西医结合急救杂志, 2018, 25(6): 646-649.
    田鑫, 刘志军, 常峥. 荣筋活血汤联合射频髓核消融术治疗盘源性腰痛的临床观察[J]. 山东中医杂志, 2016, 35(7): 618-620.
    常有军, 邱恒, 马天洪. 身痛逐瘀汤对大鼠变性腰椎间盘内TNF-α、IL-1α、IL-6、MMP-3的影响[J]. 西部医学, 2017, 29(8): 1046-1050.
    杨剑, 康建平, 冯大雄, 等. IL-1和IL-6的表达增强且与盘源性下腰痛改良日本骨科学会(mJOA)评分负相关[J]. 细胞与分子免疫学杂志, 2016, 32(1): 88-91.
    刘剑, 黄昌林, 常祺, 等. 0期诊断技术对军事训练所致椎间盘源性下腰痛患者血清IL-1β, 6-keto-PGF1α及TNF-α水平的影响及其意义[J]. 现代生物医学进展, 2017, 17(9): 1753-1757.
  • 期刊类型引用(6)

    1. 李月轩,王晓东,陈玮玮,田晓阳,闫鑫,李士学,裴世深. 靶点射频热凝术联合臭氧消融术治疗椎间盘源性腰痛的临床研究. 中国中医骨伤科杂志. 2025(01): 65-68+73 . 百度学术
    2. 孙金国. 罗哌卡因复合右美托咪定局部浸润麻醉对后路腰椎椎间融合术术后患者的影响. 反射疗法与康复医学. 2024(16): 86-88 . 百度学术
    3. 华海倩,李现林,张也. 通痹舒筋丸联合腰腹肌功能锻炼护理对椎间盘源性腰痛患者的影响. 护理实践与研究. 2022(18): 2685-2688 . 百度学术
    4. 孙晓飞,张子甲,田军涛. 低温等离子射频联合硬膜外阻滞治疗腰椎间盘突出症疗效观察. 医药论坛杂志. 2021(02): 94-97 . 百度学术
    5. 贺红庆,张士铭,朱丽霞. 强离子隙对扩张型心肌病患者发生心力衰竭的预测效果. 医药论坛杂志. 2021(05): 107-110 . 百度学术
    6. 刘姣,谭波涛,虞乐华. 腰椎间盘突出症的治疗研究进展. 保健医学研究与实践. 2020(03): 82-86 . 百度学术

    其他类型引用(2)

计量
  • 文章访问数:  261
  • HTML全文浏览量:  61
  • PDF下载量:  6
  • 被引次数: 8
出版历程
  • 收稿日期:  2019-12-05
  • 网络出版日期:  2020-08-26

目录

    /

    返回文章
    返回