Observation on therapeutic efficacy of moxibustion on umbilicus and Qiwei Baizhu Powder on diarrheal irritable bowel syndrome differentiated as spleen deficiency and dampness
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摘要:目的 观察灸脐联合七味白术散治疗脾虚湿盛型腹泻型肠易激综合征（IBS-D）的临床效果。方法 选取符合诊断及纳入标准的脾虚湿盛型IBS-D患者60例，按随机法分为观察组与对照组，每组30例。观察组采用灸脐联合七味白术散治疗，对照组采用匹维溴铵治疗。治疗4周为1个疗程。治疗前后分别评估IBS-D中医证候积分，治疗结束后第1、2、3个月对患者进行随访，观察患者复发情况。结果 治疗后，2组腹泻、肠鸣、腹痛等症状均有所改善，观察组IBS-D中医证候积分低于对照组，差异有统计学意义（P < 0.05）。观察组治疗总有效率为90.00%，高于对照组的43.33%，差异有统计学意义（P < 0.05）。观察组复发率低于对照组，差异有统计学意义（P < 0.05）。结论 治疗脾虚湿盛型IBS-D患者，灸脐联合七味白术散与单纯口服匹维溴铵比较疗效更佳，能有效降低治疗后复发率，缓解患者痛苦。Abstract:Objective To observe the clinical effect of moxibustion on umbilicus and Qiwei Baizhu Powder on diarrheal irritable bowel syndrome(IBS-D)differentiated as spleen deficiency and dampness.Methods A total of 60 patients with IBS-D differentiated as spleen deficiency and dampness who met the diagnosis and inclusion criteria were selected. The observation group was treated with moxibustion and Qiwei Baizhu Powder, and the control group was treated with pinaverium bromide. The treatment lasted for 4 weeks as a course. The TCM syndrome score of IBS-D was evaluated before and after treatment, and the patients were followed up for 1 month, 2 and 3 months after treatment, and the recurrence conditions of these patients were observed.Results After treatment, diarrhea, borborygmus, abdominal pain and other symptoms were improved in both groups, and the TCM syndrome score of IBS-D in the observation group was lower than that in the control group, the differences were statistically significant (P < 0.05). The total effective rate of the observation group was 90.00%, which was significantly higher than 43.33% of the control group (P < 0.05). The recurrence rate of the observation group was significantly lower than that of the control group(P < 0.05).Conclusion Moxibustion on umbilicus and Qiwei Baizhu Powder has better clinical efficacy than simple oral administration of pinaverium bromide in patients with IBS-D differentiated as spleen deficiency and dampness, which can effectively reduce the recurrence rate after treatment, and relieve the pain of IBS-D patients.
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