Effect of western medicine combined with traditional Chinese medicine in the treatment of sudden deafness
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摘要: 目的 探讨西医联合中医活血通窍法治疗突发性聋的效果。 方法 选取68例突发性聋患者为研究对象,采用电脑随机分组法将其分为2组,各34例。对照组采用西医基础治疗,观察组采用西医联合中医活血通窍法治疗。比较2组患者治疗前后纯音测听(PTA)阈值、血液流变学指标、疗效和不良反应发生率。 结果 治疗前, 2组患者PTA阈值、红细胞压积、纤维蛋白原、血浆黏度无显著差异(P>0.05); 治疗后,观察组PTA阈值为(40.53±8.14)dB, 显著低于对照组的(48.75±9.26)dB(P<0.05); 观察组红细胞压积为(37.51±4.26)%, 纤维蛋白原为(3.85±0.82)g/L, 血浆黏度为(1.30±0.27)mPa·s, 均显著低于对照组的(44.58±4.13)%、(4.63±0.91)g/L、(1.56±0.28)mPa·s(P<0.05); 观察组总有效率为91.18%, 显著高于对照组的70.59%(P<0.05)。观察组不良反应发生率与对照组比较,差异无统计学意义(P>0.05)。 结论 西医基础治疗联合中医活血通窍法治疗突发性聋可有效促进患者听力恢复,改善血液流变学指标,提升治疗疗效及安全性。Abstract: Objective To investigate the effectiveness of western medicine combined with traditional Chinese medicine with invigorating blood circulation and unblocking orifice in the treatment of sudden deafness. Methods A total of 68 sudden deafness patients were selected, and were divided into two groups according to computer random grouping method. Control group(n=34)was treated with basic treatment by western medicine, while the observation group(n=34)was additionally treated by traditional Chinese medicine with invigorating blood and unblocking orifice on the basis of western medicine. Pure tone audiometry(PTA)threshold, blood rheological indicators, curative effect and adverse reaction rates of two groups before and after treatment were compared. Results There were no significant differences in PTA threshold, hematokrit, fibrinogen and plasma viscosity between the two groups before treatment(P>0.05). After treatment, the PTA threshold of the observation group was(40.53±8.14)dB, which was lower than(48.75±9.26)dB in the control group(P<0.05). The values of hematokrit, fibrinogen and the plasma viscosity were(37.51±4.26)%,(3.85±0.82)g/L and(1.30±0.27)mPa·s, respectively, which were significantly lower than(44.58±4.13)%,(4.63±0.91)g/L, and(1.56±0.28)mPa·s, respectively of the control group(P<0.05). The total effective rate of the observation group was significantly higher than that of the control group(91.18% vs. 70.59%, P<0.05). The incidence of adverse reactions in the two groups showed no significant difference(P>0.05). Conclusion Basic treatment of western medicine combined with - traditional Chinese medicine with invigorating blood circulation and unblocking orifice in the treatment of sudden deafness can effectively promote hearing recovery, improve hemorheological indicators, and enhance the treatment efficacy and safety.
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