Effect of Qishen Yiqi Dropping Pills on cardiac function in patients with chronic heart failure
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摘要: 目的 探讨芪参益气滴丸对心力衰竭患者心功能的改善效果。 方法 选取200例慢性心力衰竭患者为研究对象,根据入院顺序分为2组,其中观察组100例患者接受芪参益气滴丸治疗,对照组100例患者接受常规治疗。比较2组N末端脑利钠肽前体(NT-proBNP)、血清促生长因子1(IGF-1)、肌钙蛋白T(cTnT)、心功能指标以及治疗效果、中医证候积分。 结果 2组治疗后血浆NT-proBNP、IGF-1、cTnT水平比较,差异有统计学意义(P<0.05); 2组心功能指标比较,差异有统计学意义(P<0.05); 观察组治疗总有效率显著高于对照组(P<0.05); 观察组治疗后中医证候积分为(1.21±1.03)分,显著低于对照组的(3.98±1.65)分(P<0.05)。 结论 芪参益气滴丸能够显著改善慢性心力衰竭患者的心功能,且安全性较高。Abstract: Objective To study effect of Qishen Yiqi Dropping Pills in improvement of cardiac function of heart failure patients. Methods A total of 200 patients with chronic heart failure were selected as research objects, and were divided into two groups according to their admission order. One hundred patients treated by Qishen Yiqi Dripping Pills were selected as observation group, and another one hundred patients treated by routine method were included in control group. The levels of N-terminal pro-brain natriuretic peptide(NT-proBNP), insulin-like growth factor 1(IGF-1), cardiac troponin T(cTnT), cardiac function indexes, therapeutic effect and Traditional Chinese Medicine syndrome score were compared between the two groups. Results After treatment, the levels of NT-proBNP, IGF-1 and cTnT showed significant differences in the two groups(P<0.05). There were statistical differences in cardiac function indexes in two groups(P<0.05). The total effective rate in the observation group was significantly higher than that in the control group(P<0.05). After treatment, the traditional Chinese medicine syndrome score was(1.21±1.03)in the observation group, which was significantly lower than(3.98±1.65)in the control group(P<0.05). Conclusion Qishen Yiqi Dropping Pills are of great significance in improving the cardiac function of chronic heart failure, and has higher safety.
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