男性乳腺肿瘤患者临床病理特征及超声影像特点分析

汤蕾, 符德元

汤蕾, 符德元. 男性乳腺肿瘤患者临床病理特征及超声影像特点分析[J]. 实用临床医药杂志, 2020, 24(18): 13-17. DOI: 10.7619/jcmp.202018004
引用本文: 汤蕾, 符德元. 男性乳腺肿瘤患者临床病理特征及超声影像特点分析[J]. 实用临床医药杂志, 2020, 24(18): 13-17. DOI: 10.7619/jcmp.202018004
TANG Lei, FU Deyuan. Male breast neoplasms: analysis in clinicopathological features and ultrasonic manifestations[J]. Journal of Clinical Medicine in Practice, 2020, 24(18): 13-17. DOI: 10.7619/jcmp.202018004
Citation: TANG Lei, FU Deyuan. Male breast neoplasms: analysis in clinicopathological features and ultrasonic manifestations[J]. Journal of Clinical Medicine in Practice, 2020, 24(18): 13-17. DOI: 10.7619/jcmp.202018004

男性乳腺肿瘤患者临床病理特征及超声影像特点分析

详细信息
    通讯作者:

    符德元, E-mail: fdy1003@163.com

  • 中图分类号: R737.9

Male breast neoplasms: analysis in clinicopathological features and ultrasonic manifestations

  • 摘要: 目的 分析男性乳腺肿瘤的临床病理特征以及超声影像特点。 方法 回顾性分析江苏省苏北人民医院甲状腺乳腺外科收治的28例男性乳腺肿瘤患者的临床资料。 结果 28例男性乳腺肿瘤患者中, 15例出现皮肤侵犯或乳头溢液后就诊, 12例患者病程1年以上, 4例患者未完成后续治疗。19例男性乳腺癌患者(MBC)患者中, 15例(78.9%)超声表现为低回声, 3例(15.8%)表现为钙化, 6例(31.6%)出现血流信号。16例(84.2%)MBC患者原发部位位于中央, MBC组与非MBC组原发部位差异有统计学意义(P<0.05)。 结论 男性乳腺肿瘤患者普遍就医晚,治疗依从性差。MBC大多位于中央部,低回声、钙化、血流信号为常见的超声表现,这些超声表现有助于男性乳腺良恶性肿瘤的鉴别和诊断。
    Abstract: Objective To analyze the clinicopathological features and ultrasonic manifestations of male breast neoplasms. Methods The clinical data of 28 male patients with breast neoplasms in Subei People's Hospital in Jiangsu Province was retrospectively analyzed. Results Out of 28 male patients with breast neoplasms, fifteen patients visited doctors after developing symptoms of nipples discharge, and twelve patients had a duration of more than 1 year. At the same time, four of them did not complete further treatment. Out of nineteen male breast cancer(MBC)patients, the following ultrasonic manifestations were noticed: fifteen cases(78.9%)showed hypo echoic mass, three cases(15.8%)showed calcification and six cases(31.6%)showed increased focal vascularity. The primary site of MBC patients was located in the central portion in 16 cases(84.2%). The primary site of MBC group and non-MBC group showed significant difference(P<0.05). Conclusion Male patients are likely to reluctant to see a doctor early and have poor compliance to treatment. The primary site of MBC is mostly located in the central portion and manifestations of ultrasound images include hypo-echoic mass, calcification and increased focal vascularity, which could be helpful for differential diagnosis between benign and malignant male breast neoplasms.
  • LEON-FERRE R A, GIRIDHAR K V, HIEKEN T J, et al. A contemporary review of male breast cancer: current evidence and unanswered questions[J]. Cancer Metastasis Re, 2018, 37(4): 599-614.

    VENIGALLA S, CARMONA R, GUTTMANN D M, et al. Use and Effectiveness of Adjuvant Endocrine Therapy for Hormone Receptor-Positive Breast Cancer in Men[J]. JAMA Oncol, 2018, 4(10): e181114.

    LOSURDO A, ROTA S, GULLO G, et al. Controversies in clinicopathological characteristics and treatment strategies of male breast cancer: A review of the literature[J]. Crit Rev Oncol Hematol, 2017, 113: 283-291.

    姜英, 常晓燕, 陈杰. 乳腺颗粒细胞瘤7例临床病理分析[J]. 诊断病理学杂志, 2016, 23(9): 647-649.

    XIAO K, ZHAO Y, CAI Y, et al. The effect of marital status on the survival of patients with colorectal neuroendocrine neoplasms: an analysis of the SEER database[J]. Rev Esp Enferm Dig, 2020, 112(2): 109-117.

    SEVERSON T M, ZWART W. A review of estrogen receptor/androgen receptor genomics in male breast cancer[J]. Endocr Relat Cancer, 2017, 24(3): R27-R34.

    RUKANSKIENÉ D, VEIKUTIS V, JONAITIENÉ E, et al. Preoperative Axillary Ultrasound versus Sentinel Lymph Node Biopsy in Patients with Early Breast Cancer[J]. Medicina(Kaunas), 2020, 56(3): 127-133.

    余丽惠, 罗葆明. 超声诊断乳腺癌腋窝淋巴结转移研究进展[J]. 中国医学影像技术, 2015, 31(5): 793-796.
    石祥呈, 屈重霄, 林瀛, 等. 10例乳腺颗粒细胞瘤临床病理分析[J]. 中国实用医刊, 2019(11): 8-10.

    DE SIMONE N, AGGON A, CHRISTY C. Granular cell tumor of the breast: clinical and pathologic characteristics of a rare case in a 14-year-old girl [J]. J Clin Oncol, 2011, 29(22): e656-e657.

    CORSO G, DI NUBILA B, CICCIA A, et al. Granular cell tumor of the breast: Molecular pathology and clinical management[J]. Breast J, 2018, 24(5): 778-782.

    DI LAURO L, BARBA M, PIZZUTI L, et al. Androgen receptor and antiandrogen therapy in male breast cancer[J]. Cancer Lett, 2015, 368(1): 20-25.

    MUKENDI A M, VAN DEN BERG E, PATHER S, et al. Metachronous or synchronous male breast and prostate cancers a duality to lookout for[J]. F1000 Res, 2018, 7: 1825-1834.

    OTTINI L. Male breast cancer: a rare disease that might uncover underlying pathways of breast cancer[J]. Nat Rev Cancer, 2014, 14(10): 643-649.

    ABHYANKAR N, HOSKINS K F, ABERN M R, et al. Descriptive characteristics of prostate cancer in patients with a history of primary male breast cancer-a SEER analysis[J]. BMC Cancer, 2017, 17(1): 659-667.

  • 期刊类型引用(1)

    1. 徐庆梅,王晓红,徐国新. 术中冰冻病理在乳腺肿瘤诊断中的应用及常见诊断陷阱. 中国医药指南. 2025(05): 109-111 . 百度学术

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  • 收稿日期:  2020-07-14

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