超敏C反应蛋白对冠心病介入治疗患者预后的预测作用

Value of hypersensitivity C-reactive protein in predicting the prognosis of coronary heart disease patients with interventional therapy

  • 摘要: 目的 观察超敏C反应蛋白(hs-CRP)预测冠心病介入治疗患者预后的效果。 方法 选取本院收治的冠心病患者240例为观察组,行冠状动脉介入治疗; 选取同期冠状动脉造影患者260例为对照组。所有受检者均采集血清行hs-CRP检测。观察组定期到院复查,统计不良事件发生率。 结果 观察组介入术前hs-CRP水平显著高于对照组(P<0.05), 介入术后hs-CRP水平显著高于介入术前(P<0.05)。hs-CRP≥3 ng/L组患者的不良心血管事件发生率为13.66%, 显著高于hs-CRP<3 mg/L组患者的2.53%(P<0.05)。 结论 冠心病介入治疗后患者存在显著的局部炎症反应,检测血清hs-CRP水平对预后评估具有一定的预测作用。

     

    Abstract: Objective To observe the significance of hypersensitivity C-reactive protein(hs-CRP)in predicting the prognosis of coronary heart disease patients with interventional therapy. Methods A total of 240 coronary heart disease patients in our hospital were selected as observation group(given percutaneous coronary intervention), and 260 coronary angiography patients were selected as control group during the same period. The serum of all recruiters were collected for detection of levels of hs-CRP. Patients in the observation group had regular visits in the hospital, and its incidence of adverse events was recorded. Results Compared with the control group, the level of hs-CRP in the observation group was significantly higher(P<0.05). Compared with preoperation, hs-CRP level after intervention was significantly higher(P<0.05). The incidence of adverse cardiovascular events in hs-CRP ≥3 ng/L group was significantly higher than hs-CRP <3 mg/L(13.66% versus 2.53%, P<0.05). Conclusion Patients with coronary heart disease have obvious local inflammatory response after interventional therapy. Detection of serum hs-CRP level has a certain effect in prediction of prognosis.

     

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