促排卵周期宫腔内人工授精后妊娠失败的影响因素分析

黄素花; 徐丽爽; 毛薇; 张昀

doi:10.7619/jcmp.20201901

促排卵周期宫腔内人工授精后妊娠失败的影响因素分析

Analysis of influencing factors of pregnancy failure after intrauterine insemination during ovulation promoting cycle

摘要

摘要:
目的探讨促排卵周期宫腔内人工授精（IUI）后妊娠失败的影响因素。
方法选择完成促排卵周期IUI的200例患者及其配偶为研究对象。观察患者临床妊娠结局；自制调查问卷，记录患者相关资料；分析促排卵周期IUI后妊娠失败的影响因素。
结果 151例患者促排卵周期IUI后妊娠失败，妊娠失败率为75.50%。肥胖、子宫内膜异位症（EMs）、焦虑/抑郁均是促排卵周期IUI后妊娠失败的影响因素（OR>0，P < 0.05）。
结论促排卵周期IUI后患者妊娠失败风险高，可能与肥胖、EMs、焦虑/抑郁等因素有关，临床应及时评估风险因素，并针对性实施干预，提高IUI后妊娠率。

Abstract:
Objective To explore the influencing factors of pregnancy failure after intrauterine insemination (IUI) during ovulation induction cycle.
Methods Two hundred patients and their spouses who completed the ovulation induction cycle IUI were selected as the research subjects. The clinical pregnancy outcomes of patients were observed; self-made questionnaires were used to record relevant data of patients; the influencing factors of pregnancy failure after ovulation induction cycle IUI were analyzed.
Results Pregnancy failure after ovulation induction cycle IUI was observed in 151 patients, and the pregnancy failure rate was 75.50%. Obesity, endometriosis (EMs) and anxiety or depression were all the influencing factors of pregnancy failure after IUI during ovulation promoting cycle (OR>0, P < 0.05).
Conclusion The risk of pregnancy failure is high after IUI treatment during ovulation promoting cycle, which may be related to obesity, EMs, anxiety or depression and other factors. Clinical evaluation of risk factors should be timely performed, and targeted interventions should be implemented to improve the pregnancy rate after IUI.

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