补肾活血汤治疗非肥胖型多囊卵巢综合征患者的疗效及对中医证候积分、卵巢功能的影响

Effects of Bushen Huoxue Decoction for patients with non-obese polycystic ovary syndrome and its effects on score of traditional Chinese medicine syndrome and ovarian function

  • 摘要: 目的 探讨补肾活血汤治疗非肥胖型多囊卵巢综合征(PCOS)患者的疗效及对中医证候、卵巢功能的影响。 方法 选取92例非肥胖型PCOS患者为研究对象,采用随机数字表法分为2组。对照组(n=46)采用克罗米芬治疗,观察组(n=46)在此基础上联合补肾活血汤治疗。比较2组治疗效果,记录2组治疗前后中医证候积分、促卵泡激素(FSH)水平及卵巢功能恢复情况。 结果 观察组总有效率为95.65%, 高于对照组的80.43%, 差异有统计学意义(P<0.05); 治疗后, 2组中医证候积分下降, FSH水平升高,观察组中医证候积分低于对照组, FSH水平高于对照组,差异均有统计学意义(P<0.05); 治疗后, 2组卵泡数、卵巢体积均下降,且观察组优于对照组,差异有统计学意义(P<0.05)。 结论 补肾活血汤治疗非肥胖型PCOS患者效果显著,可有效改善中医证候积分及卵巢功能,提高促卵激素水平。

     

    Abstract: Objective To explore the therapeutic effects of Bushen Huoxue Decoction in patients with non-obese polycystic ovary syndrome(PCOS), and its effects on score of traditional Chinese medicine syndrome and ovarian function. Methods A total of 92 non-obese PCOS patients were selected as research subjects, and were divided into two groups according to random number table method. The control group(n=46)was treated with clomiphene, while the observation group(n=46)additionally received Bushen Huoxue Decoction based on the control group. The curative effect after treatment was compared, and the scores of traditional Chinese medicine syndrome, fdlicle stimulatine hormone(FSH)levels and recovery condition of ovarian function before and after treatment were recorded. Results The total effective rate of the observation group was significantly higher than that of the control group(95.65% versus 80.43%, P<0.05); after treatment, the traditional Chinese medicine syndrome scores of the two groups decreased, and FSH levels increased. The observation group had significantly lower traditional Chinese medicine syndrome score and higher level of FSH than those of the control group(P<0.05). After treatment, the number of follicles and ovarian volume of both groups were decreased, and the observation group had significantly better results than the control group(P<0.05). Conclusion Bushen Huoxue Decoction has better efficacy in treating non-obese PCOS patients, which can effectively improve the traditional Chinese medicine syndromes as well as ovarian function, and increase the level of ovarian stimulating hormone.

     

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