Abstract: Objective To observe the clinical effect of imbedding needle on accelerated recovery after minimally invasive surgery for breast mass. Methods Sixty patients undergoing elective minimally invasive resection of breast masses were randomly divided into control group and imbedding needle group, with 30 cases in each group. The control group received routine perioperative nursing guidance, while the imbedding needle group received imbedding needle therapy and routine care. The Visual Analogue Scale(VAS)scores at 1, 2, 4, 6, 8 and 24 h postoperation as well as number of patients with remedial treatment were compared between the two groups. The quality of recovery was evaluated by Quality of Recovery 40(QoR-40)at 24 h postoperation, and Multidimensional Fatigue Scale(MFI)was adopted for fatigue assessment. Results Compared with control group, the VAS scores of the imbedding needle group at 1, 2, 4, 6 and 8 h after operation were significantly lower(P<0.05). The number of patients with remedial treatment was significantly less than that in the control group(P<0.05). The total QoR-40 scores, emotion status, comfort and pain control scores were better than those in the control group at 24 h postoperation(P<0.05), but there was no statistically difference between psychological support score and self-care ability score(P>0.05). There was no significant between-group difference in MFI score(P>0.05). Conclusion Imbedding needle can alleviate early postoperative pain, improve emotional state and comfort, and promote recovery of breast mass patients with minimally invasive surgery.