急救中心驾驶员创伤后应激障碍双侧海马体积变化研究

何伟; 刘瑜; 曹志宏; 王冬青; 李月峰; 李国海; 赵天; 罗一烽

doi:10.7619/jcmp.202024009

急救中心驾驶员创伤后应激障碍双侧海马体积变化研究

1. 江苏大学附属医院, 江苏镇江, 212000;
2. 江苏大学附属宜兴医院, 江苏宜兴, 214200

基金项目:

江苏省科教强卫工程(QNRC2016207)

江苏省无锡市科技计划项目(CSZ0N1632)

ML201320)

江苏省卫计委面上项目(H201656)

江苏省无锡市卫计委科研项目(Z201610

详细信息

通讯作者:
罗一烽, E-mail: luoyifeng1207@163.com

中图分类号: R445.2;R749.5
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- 文章访问数: 442
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出版历程
- 收稿日期: 2020-10-24
- 网络出版日期: 2020-12-29

Study on changes of bilateral hippocampus volume in drivers with post-traumatic stress disorder in emergency center

1. Affiliated Hospital of Jiangsu University, Zhenjiang, Jiangsu, 2120000;
2. Yixing Hospital Affiliated to Jiangsu University, Yixing, Jiangsu, 214200

摘要

摘要: 目的观察创伤后应激障碍(PTSD)驾驶员的双侧海马体积变化。方法将15例PTSD驾驶员纳入观察组, 15例未患有PTSD驾驶员纳入对照组。2组均采用核磁共振成像(MRI)检查进行扫描。比较2组双侧海马体积变化,同时分析观察组双侧海马体积和PTSD诊断量表(CAPS)、创伤后持续时间、年龄的相关性。结果与对照组比较,观察组左侧海马体积缩小,差异有统计学意义(P<0.05)。观察组左侧海马体积与CAPS得分及创伤后持续时间呈显著负相关(P<0.05)。结论急救中心PTSD驾驶员左侧海马体积显著缩小,且左侧海马体损伤与病情严重程度、创伤后持续时间有关。
- 创伤后应激障碍 /
- 海马 /
- 体积 /
- 急救中心 /
- 驾驶员
Abstract: Objective To study changes in bilateral hippocampal volume of drivers with post-traumatic stress disorder(PTSD)in emergency center. Methods Fifteen drivers with PTSD were included in the observation group, and 15 without PTSD were included in the control group. Magnetic resonance imaging(MRI)was performed in both groups. The changes of bilateral hippocampal volume in the two groups were compared, and the correlations between bilateral hippocampal volume and clinician-administered PTSD scale(CAPS), post-traumatic duration and age in the observation group were analyzed. Results Compared with the control group, the left hippocampal volume of the observation group was significantly reduced(P<0.05). The volume of the left hippocampus was negatively correlated with CAPS scores and post-traumatic duration in the observation group(P<0.05). Conclusion The left hippocampal volume of emergency center drivers with PTSD is significantly reduced, and hippocampal damage is associated with severity of the illness and duration of post-trauma.
- post-traumatic stress disorder /
- hippocampus /
- volume /
- emergency center /
- driver

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参考文献(14)

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