Effect of modified Shipi Yin combined with acupoint application in patients with chronic heart failure differentiated as heart-yang deficiency syndrome
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摘要: 目的 探讨实脾饮加减结合穴位贴敷在慢性心力衰竭心肾阳虚证患者中的实施效果。 方法 选取122例慢性心力衰竭患者为研究对象,采用随机投掷法分为对照组和研究组。对照组实施常规西药治疗,研究组在对照组基础上实施实脾饮加减结合穴位贴敷治疗,对比2组的治疗效果。 结果 治疗前, 2组中医证候评分、6 min步行距离比较差异无统计学意义(P>0.05); 治疗后,研究组中医证候评分低于对照组, 6 min步行距离大于对照组,差异有统计学意义(P<0.05); 研究组治疗有效率为93.44%, 高于对照组的80.33%, 差异有统计学意义(P<0.05)。治疗前, 2组每搏输出量(SV)、左室射血分数(LVEF)、左心室短轴缩短率(LVFS)等心功能指标水平及血浆一氧化氮(NO)、内皮素(ET)、血浆脑钠肽(BNP)指标水平差异无统计学意义(P>0.05); 治疗后,研究组SV、LVEF、LVFS等心功能指标水平高于对照组, NO、ET、BNP水平低于对照组,差异有统计学意义(P<0.05)。 结论 实脾饮加减结合穴位贴敷治疗慢性心力衰竭心肾阳虚证患者效果显著。Abstract: Objective To explore the effect of modified Shipi Yin combined with acupoint application in patients with chronic heart failure differentiated as heart-yang deficiency syndrome. Methods A total of 122 patients with chronic heart failure were selected and divided into control group and study group according to random throwing method. The control group was treated with conventional western medicine, and the study group was treated modified with Shipi Yin combined with acupoint application on the basis of the control group, the therapeutic effects of the two groups were compared. Results There were no significant differences in the scores of traditional Chinese medicine syndrome and 6 min walking distance before treatment between the two groups(P>0.05); after treatment, the traditional Chinese Medicine syndrome score of the study group was significantly lower than that in the control group, and the 6 min walking distance was significantly greater than that in the control group(P<0.05); the effective rate in the study group was 93.44%, which was significantly higher than 80.33% in the control group(P<0.05). The levels of cardiac function indexes such as stroke volume(SV), left ventricular ejection fraction(LVEF), and left ventricular short-axis shortening rate(LVFS), plasma nitric oxide(NO), endothelin(ET), plasma brain natriuretic peptide(BNP)levels in the two groups before treatment showed no significant differences(P>0.05); after treatment, SV, LVEF and LVFS - levels in the study group were higher than those in the control group, and NO, ET, BNP indexes were lower than those in the control group, the differences were significant(P<0.05). Conclusion Modified Shipi Yin combined with acupoint application has obvious efficacy for patients with chronic heart failure differentiated as heart-yang deficiency syndrome.
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