Abstract: Objective To explore the influence of group-activity health education on social support and self-management behaviour in coronary heart disease patients with percutaneous coronary intervention(PCI). Methods Totally 67 patients with coronary heart disease after PCI from January to August 2018 were selected as experimental group, and 61 coronary heart disease patients after PCI from June to December 2017 were selected as control group. The control group was given routine health education, and the experimental group was given group-activity health education on the basis of the control group. After 6 months of follow-up, the social support, self-management behaviour, quality of life and prognosis were compared between the two groups. Results After 6 months of follow-up, the scores of subjective support, objective support, social support utilization and total social support in the experimental group were significantly higher than those in the control group(P<0.05); the scores of adverse hobby management, symptom management, disease knowledge management and therapeutic compliance management in the experimental group were significantly higher than those in the control group(P<0.05 or P<0.01); the scores of physical limitation, angina stability, therapeutic satisfaction degree and disease cognition in the experimental group were significantly higher than those in the control group(P<0.05); the incidence of cardiovascular events and readmission rate in the experimental group were significantly lower than those in the control group(P<0.05). Conclusion Group-activity health education can improve the social support level of patients with coronary heart disease after PCI, promote the development of self-management behaviour, and improve - the quality of life of patients.