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中医辨证论治对复发性鼻咽癌放疗减毒作用的临床研究

Clinical study on detoxification of radiotherapy for recurrent nasopharyngeal carcinoma by syndrome differentiation and treatment of traditional Chinese medicine

    摘要
  • 摘要:
      目的  观察中医辨证治疗对复发性鼻咽癌放疗后毒副作用的影响。
      方法  选取99例复发性鼻咽癌患者为研究对象，采用随机数字表法分为观察组（52例）和对照组（47例）。比较2组血液检测指标水平、放射性皮肤损伤程度、皮肤损伤平均治愈时间及放疗后症候发生情况。
      结果  观察组血液检测指标水平高于对照组，差异有统计学意义（P < 0.05或P < 0.01）；观察组皮肤损伤平均治愈时间短于对照组，差异有统计学意义（P < 0.05）；观察组口腔黏膜炎、胃肠道反应、口干症、张口受限发生率低于对照组，差异有统计学意义（P < 0.05）。
      结论  中医辨证论治可在一定程度减轻复发性鼻咽癌放疗的毒副作用。

     

    Abstract:
      Objective  To observe effects of TCM syndrome differentiation and treatment on the toxic and side effects of radiotherapy for recurrent nasopharyngeal carcinoma.
      Methods  A total of 99 patients with recurrent nasopharyngeal carcinoma were selected and divided into observation group (52 cases) and control group (47 cases) by random number table method. Blood test indexes, radiation skin injury level, average healing time of skin injury and occurrence of symptoms after radiotherapy were compared between the two groups.
      Results  The blood test indexes of the observation group were higher than those of the control group (P < 0.05 or P < 0.01). The average healing time of skin injury in the observation group was shorter than that in the control group (P < 0.05). The incidence of oral mucositis, gastrointestinal reaction, dry month and limitation of opening mouth in the observation group were lower than those in the control group (P < 0.05).
      Conclusion  Traditional Chinese medical syndrome differentiation and treatment can relieve toxic and side effects of radiotherapy for recurrent nasopharyngeal carcinoma.

     

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