Abstract:
Objective To compare Mini-Nutrition Assessment Form (MNA) and Prognostic Nutrition Index (PNI) in evaluating efficacy of nutritional status in elderly patients with acute cerebral infarction.
Methods The baseline data of 120 elderly patients with acute cerebral infarction were collected. The receiver operating characteristic (ROC) curve of PNI was drawn based on the prognosis of patients at 3 months as the end point. The optimal cut-off value of PNI was determined and they were divided into differed groups. Then PNI and MNA were used to evaluate the nutrition of the patients, and their relationships with anthropometric indicators, biochemical indicators and functional status indicators were analyzed by correlation analysis, and consistency of PNI and MNA methods was evaluated.
Results The optimal cut-off value of the PNI was 50.375. Of 120 patients, there were 50 (41.7%) with malnutrition by PNI and 57 (47.5%) by MNA. No significant differences were found in age, body weight, arm circumference, calf circumference, weight loss, body mass index, National Institutes of Health Stroke Scale (NIHSS) score and the total number of total lymphocyte count and total protein of two groups assessed by both MNA and PNI(P>0.05). The consistency of the two methods showed that PNI was highly consistent with MNA (κ=0.647).
Conclusion PNI and MNA have a highly consistent effect in assessing the nutritional status of elderly patients with acute cerebral infarction. PNI is a more objective indicator, while MNA is a more subjective one.