育龄期女性急性心肌梗死的危险因素及冠状动脉病变分析

Analysis in risk factors and coronary artery lesion in females of childbearing age with acute myocardial infarction

  • 摘要:
      目的  分析育龄期女性急性心肌梗死(AMI)的危险因素及冠状动脉病变特点。
      方法  回顾性分析住院治疗的101例中青年女性AMI患者的临床资料, 根据是否处于育龄期将患者分为育龄期组41例和非育龄期组60例。比较2组患者的冠状动脉粥样硬化性心脏病(简称冠心病)相关影响因素及临床指标的结果,分析育龄期女性的AMI危险因素,并比较2组患者的冠状动脉造影结果。
      结果  育龄期组患者妇科手术发生率和血清甘油三酯(TG)水平、体质量指数(BMI)均高于非育龄期组,血清低密度脂蛋白(LDL)水平则低于非育龄期组,差异均有统计学意义(P < 0.05)。2组患者冠状动脉病变情况比较,差异无统计学意义(P > 0.05)。
      结论  临床对于存在冠心病危险因素的育龄期女性应加强监测,特别是超重、血清TG水平升高以及有子宫和/或卵巢切除手术史者,应早期筛查及预防。

     

    Abstract:
      Objective  To analyze the risk factors and characteristics of coronary artery lesion in females of childbearing age with acute myocardial infarction(AMI).
      Methods  A retrospective analysis was performed for 101 middle-aged hospitalized women with AMI, and these patients were divided into childbearing age group(n=41) and non-childbearing age group(n=60) according to whether they were in childbearing age or not. The related influencing factors and clinical indicators of coronary atheroslerotic heart disease in two groups were compared. The risk factors of AMI in women of childbearing age were analyzed, and the results of coronary angiography were compared between the two groups.
      Results  The incidence of gynecological surgery, serum triglyceride (TG) level, body mass index (BMI) in the childbearing age group were higher than those in the non-childbearing age group, and serum low-density lipoprotein (LDL) level was lower than that in the non-childbearing age group(P < 0.05). There was no significant difference in coronary artery disease between two groups (P > 0.05).
      Conclusion  Early screening and prevention should be strengthened for females in childbearing age who have risk factors for coronary heart disease, especially those who are overweight, have elevated serum triglyceride levels, and those who have undergone gynecological surgery to remove the uterus and/or ovaries.

     

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