Objective  To compare the diagnostic value of Chinese-Thyroid Imaging Reporting and Data System (C-TIRADS) and American Thyroid Association (ATA) ultrasonic model in benign and malignant thyroid nodules.

  Methods  The ultrasound images of 245 patients with thyroid nodules confirmed by pathological results were analyzed retrospectively. C-TIRADS and ATA ultrasound models were used for thyroid nodules classification, respectively. The diagnostic efficacy of the two diagnostic models was compared.

  Results  The areas under the receiver operating characteristic (ROC) curves of C-TIRADS and ATA ultrasound models were 0.750 and 0.625, respectively. The sensitivity and specificity of C-TIRADS in diagnosis of benign and malignant thyroid nodules were 97.7% and 52.2%, respectively. The sensitivity and specificity of ATA ultrasound model in diagnosis of benign and malignant thyroid nodules were 99.2% and 25.7%, respectively.

  Conclusion  C-TIRADS has higher diagnostic efficacy and specificity than ATA model in diagnosis of benign and malignant thyroid nodules, which can reduce the misdiagnosis rate of benign thyroid nodules of patients.