21例肺黏膜相关淋巴组织淋巴瘤的CT和18F-氟代脱氧葡萄糖正电子发射计算机断层显像的影像学表现

CT and positron emission tomography/computed tomography using (18)F-fluorodeoxyglucose findings in 21 patients with pulmonary mucosa-associated lymphoidtissue lymphoma

  • 摘要:
    目的 探讨肺黏膜相关淋巴组织(MALT)淋巴瘤的CT和18F-氟代脱氧葡萄糖(18F-FDG)正电子发射计算机断层显像(PET)-CT的影像学表现。
    方法 回顾性分析经病理结果证实的21例肺MALT淋巴瘤患者的CT及PET-CT影像学资料,并通过Logistic回归分析探讨18F-FDG亲和力与影像学表现的相关性。
    结果 21例患者中,共发现60个肺部病灶,其中22个实变样病灶,28个结节或肿块样病灶和10个磨玻璃样病灶。12例为单发病灶,9例为多发病灶,多发病灶患者中,双侧病灶7例,单侧病灶2例。18F-FDG PET-CT显示,60个病灶中45个为高代谢病灶,15个为低代谢病灶。Logistic回归分析发现,18F-FDG亲和力与病灶形态及病灶直径相关(P<0.01)。
    结论 肺MALT淋巴瘤影像学表现多样,可为结节或肿块型、肺炎型及磨玻璃型,多为亲和18F-FDG的肿瘤,且18F-FDG亲和力与肿瘤直径及形态相关。

     

    Abstract:
    Objective To investigate imaging manifestations of CT and positron emission tomography/computed tomography (PET)-CT using (18)F-fluorodeoxyglucose (18F-FDG) in pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma.
    Methods CT and PET-CT imaging findings of 21 patients with pulmonary MALT lymphoma confirmed by pathological results were retrospectively analyzed, and the correlation between affinity of 18F-FDG and imaging findings was analyzed by Logistic regression analysis.
    Results A total of 60 pulmonary lesions were found in 21 patients, including 22 consolidation-like lesions, 28 nodular or mass-like lesions, and 10 ground-glass lesions. A total of 12 cases were single lesions and 9 cases were multiple lesions. Among the patients with multiple lesions, 7 cases were bilateral and 2 cases were unilateral lesions. 18F-FDG PET-CT showed that 45 of the 60 lesions were hypermetabolic lesions and 15 were hypometabolic lesions. Logistic regression analysis showed that 18F-FDG affinity was correlated with morphology and diameter of lesions (P<0.01).
    Conclusion The imaging manifestations of pulmonary MALT lymphoma are diverse, including nodular or mass type, pneumonic type and ground glass type. Most of them have 18F-FDG affinity that is related to tumor diameter and morphology.

     

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