255例结肠带蒂息肉内镜下表现与病理分析

Endoscopic manifestations and pathological analysis of pedunculated colonic polyps in 255 patients

  • 摘要:
    目的 分析结肠带蒂息肉内镜下表现与病理检查结果,并探讨高危息肉的危险因素。
    方法 回顾性分析天津市人民医院内镜诊疗中心收治的255例结肠带蒂息肉患者(297枚息肉)的临床特征,分析带蒂息肉的内镜下表现及病理检查结果。应用多因素Logistic回归分析研究影响结肠带蒂息肉中的高危息肉的危险因素。
    结果 不同性别及年龄患者的高危息肉占比比较,差异无统计学意义(P>0.05); 是否合并结直肠癌病史、息肉不同位置、息肉蒂不同长度、息肉不同头端直径、息肉表面是否完全充血患者的高危息肉占比比较,差异有统计学意义(P<0.05或P<0.01)。多因素Logistic回归分析显示,息肉头端直径>1~<2 cm、息肉头端直径≥2 cm和合并结直肠癌病史是高危息肉的独立危险因素。
    结论 头端越大及合并结直肠癌病史的结肠带蒂息肉患者患有高危息肉的风险越大,且发生癌变的概率更高,因此应尽早行内镜下切除术。

     

    Abstract:
    Objective To analyze the endoscopic findings and pathological results of pedunculated colonic polyps, and to discuss the risk factors for high-risk polyps.
    Methods A total of 297 pedunculated colonic polyps in 255 patients in the Endoscopic Diagnosis and Treatment Center of Tianjin People′s Hospital were retrospectively analyzed. The clinical characteristics, endoscopic manifestations and pathological results were analyzed. Multivariate Logistic regression analysis was used to study the risk factors of high risk polyps of pedunculated colonic polyps.
    Results There were no significant differences in proportions of high-risk polyps in different gender and age (P > 0.05), but there were significant differences in the proportions of high-risk polyps in patients with colorectal cancer history, differed locations, surface with or without complete congestion, different pedicle length and different tip size (P < 0.05 or P < 0.01). Multivariate Logistic regression analysis showed that the tip diameten of polyps > 1~ < 2 cm, ≥2 cm and the history of colorectal cancer were independent risk factors for high risk polyps of pedunculatedcolonic polyps.
    Conclusion Patients with larger tips of polyps and complicating with colorectal cancer history have higher risk of high-risk polyps and the higher cancerous potential risk, so endoscopic resection should be performed as early as possible.

     

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