组织工程领域中过氧化物的研究进展

古先扬; 马敏先

doi:10.7619/jcmp.20220894

组织工程领域中过氧化物的研究进展

古先扬¹,
马敏先^2, ,

1.
贵州医科大学附属口腔医院口腔修复种植科, 贵州贵阳, 550000
2.
贵州省贵阳市口腔医院口腔种植科, 贵州贵阳, 550000

基金项目:

贵州省贵阳市科技计划项目基金资助项目筑科合同[2018]1-81号

详细信息

通讯作者:
马敏先, E-mail: 562047687@qq.com

中图分类号: Q819;R34
计量
- 文章访问数: 206
- HTML全文浏览量: 112
- PDF下载量: 12
出版历程
- 收稿日期: 2022-03-21
- 网络出版日期: 2022-09-02

Research progress of peroxide in field of tissue engineering

GU Xianyang¹,
MA Minxian^2, ,

1.
Department of Prosthodontics and Implantology, Stomatological Hospital Affiliated to Guizhou Medical University, Guiyang, Guizhou, 550000
2.
Department of Oral Implantology, Guiyang City Stomatological Hospital of Guizhou Province, Guiyang, Guizhou, 550000

摘要

摘要:
在植入物与宿主整合的过程中, 如何维持细胞活力和代谢活性对于工程组织的存活和功能至关重要。过氧化物可被用作氧释放材料来减少细胞凋亡，提高工程组织存活率和成功率。过氧化物通过氧气释放对细菌产生抑制作用，释放主要机制是水解，常用的过氧化物包括过氧化钠、过氧化钙、过氧化钠和过氧化氢等。本文综述了不同类型过氧化物在骨、胰腺、心血管、皮肤、抗菌等组织方面的研究进展。
- 组织工程 /
- 组织缺氧 /
- 血管化 /
- 过氧化物 /
- 氧气释放 /
- 氧释放生物材料
Abstract:
During the integration of implants and hosts, how to maintain cell viability and metabolic activity is very important for the survival and function of engineered tissue. Peroxides can be used as oxygen releasing materials to reduce apoptosis and increase the survival and success rate of engineered tissues. Peroxides can inhibit bacteria through the release of oxygen, the main mechanism of release is hydrolysis, and commonly used peroxides include sodium peroxide, calcium peroxide, sodium peroxide and hydrogen peroxide. This paper reviewed the research progress of different types of peroxides in bone, pancreas, cardiovascular, skin, antibacterial and other tissues.
- tissue engineering /
- tissue hypoxia /
- vascularization /
- peroxides /
- oxygen release /
- oxygen release biomaterials

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