Research progress of estimated plasma volume in heart failure
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摘要:
充血可能由过度的神经激素激活引起, 表现为外周水肿和肺水肿,是影响心力衰竭(HF)患者预后的重要因素之一。因此,识别充血对诊断HF具有重要的临床意义。目前,临床评估充血的方法有限。估算的血浆容量(ePVS)被认为可用于评估充血,其具有无创性、可重复性。ePVS基于常规变量(体质量、血红蛋白及红细胞比容)的公式(Strauss公式、Duarte公式、Hakim公式)进行计算。本文就ePVS的研究进展进行综述,并讨论未来监测ePVS的临床研究方向。
Abstract:Hyperemia may be caused by excessive neurohormonal activation and is manifested as peripheral edema and pulmonary edema, which is one of the important factors affecting the prognosis of patients with heart failure (HF). Therefore, recognition of hyperemia is of great clinical significance in diagnosis HF. Currently, clinical methods for assessing hyperemia are limited. Estimated plasma volumes (ePVS) are considered to be noninvasive and reproducible for assessing hyperemia. EPVS was calculated based on the formula (Strauss, Duarte and Hakim formulas) of conventional variables (body mass, hemoglobin and erythrocyte volume). This article reviewed the progress of ePVS research and discussed the direction of clinical research in monitoring ePVS in the future.
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Keywords:
- hyperemia /
- heart failure /
- plasma volume /
- capacity management /
- prognosis
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