肠道微生物与炎症性肠病研究的可视化分析

黎俚敏; 胡昕月; 罗莲; 李爱玲; 钟晓琳

doi:10.7619/jcmp.20223426

肠道微生物与炎症性肠病研究的可视化分析

黎俚敏¹,
胡昕月¹,
罗莲¹,
李爱玲^{2, 3},
钟晓琳^1, ,

1.
西南医科大学附属医院消化内科, 四川泸州, 646000
2.
西南医科大学公共卫生学院, 四川泸州, 646000
3.
西南医科大学循证医学中心, 四川泸州, 646000

基金项目:

国家自然科学基金资助项目 82100632

详细信息

通讯作者:
钟晓琳, E-mail: zhongxl519@hotmail.com

中图分类号: R574;R319
计量
- 文章访问数: 179
- HTML全文浏览量: 42
- PDF下载量: 15
出版历程
- 收稿日期: 2022-11-14
- 修回日期: 2023-02-08
- 网络出版日期: 2023-05-24
- 刊出日期: 2023-05-14

Visualization analysis in studies of gut microbes and inflammatory bowel disease

1.
Department of Gastroenterology, the Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, 646000
2.
School of Public Health, Southwest Medical University, Luzhou, Sichuan, 646000
3.
Center for Evidence-based Medicine, Southwest Medical University, Luzhou, Sichuan, 646000

摘要

摘要:
目的
分析2013年1月—2022年10月肠道微生物与炎症性肠病(IBD)的研究热点和发展趋势。
方法
通过Web of Science检索关于肠道微生物与IBD的文献，采用可视化软件CiteSpace、VOSviewer进行分析。
结果
共检索到1 041篇文献，排除重复文献后，共纳入1 040篇。2021年发文数量达到最高峰。肠道微生物与IBD研究的主要研究者是XAVIER R J, 共发表13篇文献。美国是发文量最多的国家，哈佛大学是发文最多的机构, PLoS One是该领域发表文献最多的期刊。“IBD”“克罗恩病”“肠道菌群”为该领域研究热点; “肠道屏障”“疗效”“稳态”为该领域研究前沿。
结论
肠道微生物与IBD研究领域发展前景良好，该领域的研究可为IBD的治疗提供新思路。
- 肠道微生物 /
- 炎症性肠病 /
- 文献计量学 /
- 可视化分析 /
- CiteSpace软件 /
- VOSviewer软件
Abstract:
Objective
To analyze the research hotspot and development trend of intestinal microbes and inflammatory bowel disease (IBD) from from January 2013 to October 2022.
Methods
Literature on intestinal microbes and IBD was retrieved through Web of Science, and analyzed by visualization software CiteSpace and VOSviewer.
Results
A total of 1 041 literatures were retrieved and 1 040 were included after excluding duplicates. The number of publications reached its peak in 2021. XAVIER R J was the main researcher of the study on intestinal microbes and IBD, and a total of 13 papers had been published. The United States was the country with the most publications, Harvard University was the institution with the most publications, and PLoS One was the journal with the most publications in the field. The "IBD" "Crohn′s disease" and "intestinal flora" were hot topics in this field, and "Intestinal barrier" "curative effect" as well as "homeostasis" were the research frontiers in this field.
Conclusion
The research on intestinal microbiome and IBD has a good prospect, and the research in this field can provide new ideas for the treatment of IBD.
- gut microbes /
- inflammatory bowel disease /
- bibliometrics /
- visual analysis /
- CiteSpace software /
- VOSviewer software

HTML全文

图 1 肠道微生物与IBD研究的发文量的变化趋势

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图 2 肠道微生物与IBD研究的国家可视化图谱

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图 3 肠道微生物与IBD研究的发文机构的可视化图谱

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图 4 肠道微生物与IBD研究的作者合作可视化图谱

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图 5 关键词共现可视化图谱

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图 6 肠道微生物与IBD相关研究的35个突现关键词

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表 1 肠道微生物与IBD研究的发文量前10的国家

排名	国家	发文量	总被引频次	篇均被引次数	占比/%
1	美国	379	27 138	71.60	36.44
2	中国	294	6 340	21.56	28.27
3	加拿大	83	4 024	48.48	7.98
4	德国	66	3 773	57.17	6.35
5	英国	53	2 990	56.42	5.10
6	日本	48	1 563	32.56	4.62
7	荷兰	47	2 870	61.06	4.52
8	澳大利亚	43	1 758	40.88	4.13
8	法国	43	2 360	54.88	4.13
10	意大利	42	1 285	30.60	4.04

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表 2 肠道微生物与IBD研究中心度前10的国家

排名	国家	年份	中心度	发文量/篇
1	美国	2013	0.39	379
2	荷兰	2013	0.24	47
3	英国	2013	0.16	53
4	中国	2013	0.14	294
5	德国	2013	0.13	66
5	西班牙	2013	0.13	24
7	加拿大	2013	0.11	83
7	意大利	2013	0.11	42
9	日本	2013	0.10	48
10	澳大利亚	2013	0.07	43

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表 3 肠道微生物与IBD研究中心度排名前5的机构

排名	机构	年份	中心度	发文量/篇
1	Univ Calif San Diego	2018	0.13	10
2	Sun Yat Sen Univ	2016	0.10	14
2	Shanghai Jiao Tong Univ	2017	0.10	11
4	Katholieke Univ Leuven	2020	0.09	5
5	Harvard Med Sch	2016	0.08	19

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表 4 发文量和被引频次排名前6的作者

排名	作者	发文量/篇	排名	作者	共被引频次/次
1	RAMNIK J XAVIER	13	1	HARRY SOKOL	241
2	EUGENE B CHANG	10	2	R BALFOUR SARTOR	191
2	HUTTENHOWER CURTIS	10	3	ALEXANDER SWIDSINSKI	171
4	WILLEM M DE VOS	8	4	J GREGORY CAPORASO	159
4	ROB KNIGHT	8	4	DANIEL N FRANK	159
4	JAMES VERSALOVIC	8	6	PETER J TURNBAUGH	157

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表 5 发文量排名前10位的基金资助机构

排名	基金资助机构	发文量/篇	构成比/%
1	United States Department Of Health Human Services	259	24.90
2	National lnstitutes Of Health Nih Usa	257	24.71
3	National Natural Science Foundation Of China Nsfc	164	15.77
4	Nih National lnstitute Of Diabetes Digestive Kidney Diseases Niddk	111	10.67
5	Nih National lnstitute Of Allergy Infectious Diseases Niaid	64	6.15
6	European Commission	57	5.48
7	Nih National Cancer Institute Nci	47	4.52
8	Nih National lnstitute Of General Medical Sciences Nigms	42	4.04
9	German Research Foundation Dfg	30	2.88
10	Uk Research lnnovation Ukri	24	2.31

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表 6 微生物与IBD相关研究的发文前5位期刊的各项指标

排名	期刊	发文量/篇	被引频次/次	篇均被引次数/次	2021年影响因子	JCR分区
1	PLoS One	47	1 669	35.51	3.752	Q2
2	Inflammatory Bowel Disease	36	1 678	46.61	7.29	Q1
3	Frontiers in Microbiology	31	774	24.97	6.064	Q1
4	Gastroenterology	29	4 256	146.76	33.883	Q1
5	Gut Microbes	25	941	37.64	9.434	Q1

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表 7 研究中排名前10位的关键词

排名	关键词	频次/次	中心度
1	inflammatory bowel disease	556	0.01
2	Crohn′s disease	286	0.02
3	gut microbiota	263	0.02
4	ulcerative colitis	259	0.03
5	bacteria	103	0.02
6	expression	97	0.02
7	diversity	93	0.03
8	fecal microbiota	86	0.03
8	intestinal microbiota	86	0.03
10	pathogenesis	78	0.02

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