Objective To explore the diagnostic value of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and signal intensity-time (SI-T) curve in benign and malignant prostate lesions.

Methods A total of 102 patients with prostate disease were selected as the study objects, and were divided into benign group (65 cases) and malignant group (37 cases). Receiver operating characteristic (ROC) curve was used to analyze the diagnostic value of DCE-MRI, SI-T alone and their combined detection in benign and malignant prostate lesions.

Results The volume transfer constant (Ktrans), rate constant (Kep) and extravascular extracellular space volume fraction (Ve) of patients in the malignant group were higher than those in the benign group (P < 0.05). The proportion of fast growth and slow decline of SI-T curve in the malignant group was significantly higher than that in the benign group, and the proportion of continuous slow rise and slow rise platform type was significantly lower than that in the benign group (P < 0.05). The peak time of the malignant group was significantly shorter than that of the benign group, and the degree and rate of reinforcement were significantly higher than those of the benign group (P < 0.05). The area under the curve (AUC) of the combined detection of DCE-MRI or SI-T curve parameter in the diagnosis of benign and malignant prostate lesions was greater than that of the single detection of DCE-MRI or SI-T curve parameter (P < 0.05).

Conclusion The combined detection of DCE-MRI and SI-T curve has good diagnostic value in diagnosis of benign and malignant prostate lesions.